a, a N Clinical Trials
A listing of a, a N clinical trials actively recruiting patients volunteers.
Found 2490 clinical trials
SPEARHEAD 2 Study in Subjects With Recurrent or Metastatic Head and Neck Cancer
This is a study to investigate the efficacy and safety of ADP-A2M4 in combination with pembrolizumab in HLA-A*02 eligible and MAGE-A4 positive subjects with recurrent or metastatic Head and Neck cancer.
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- 05 Aug, 2020
Upper Limb Loss Perturbation Response
Recent investigations have suggested that persons with upper limb loss experience a high prevalence of falls with a quarter of reported falls resulting from a trip. Moreover, studies indicate that missing part of an arm may negatively impact balance and that use of a prosthesis exacerbates this problem.
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- 16 Feb, 2024
- 1 location
INO-3107 With Electroporation (EP) in Participants With HPV-6- and/or HPV-11-Associated Recurrent Respiratory Papillomatosis (RRP)
A safety run-in will be performed with up to six participants across cohort A and B with a one week waiting period between each enrolled participant.
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- 05 Aug, 2020
Do Implementation Intentions Increase Average Daily Step Count.
This study seeks to compare the increase in steps in participants randomly assigned in a 2:2:1 allocation to a goal-setting pedometer intervention, a goal-setting plus implementation intentions pedometer intervention vs pedometer only.
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- 16 Feb, 2024
- 1 location
Prevention of Infection and Incidence of COVID-19 in Medical Personnel Assisting Patients With New Coronavirus Disease
This is a randomized controlled trial of the efficacy and safety evaluation of oral administration of Bromhexine hydrochloride for the prevention of SARS-CoV-2 infection and COVID-19 disease in medical personnel assisting patients with a new coronavirus disease
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- 16 Feb, 2024
- 1 location
4SCAR-T Therapy Post CD19-targeted Immunotherapy
Clinical response and optiminzation of a standardized lentiviral vector and cell production protocol will be investigated. This is a phase I/II trial enrolling patients from multiple clinical centers.
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- 05 Aug, 2020
Neoadjuvant Irradiation of Retroperitoneal Soft Tissue Sarcoma With Ions Retro-Ion
The study is a randomized, open, prospective phase II study. The aim of the study is to evaluate the safety and feasibility of a hypofractionated, accelerated radiation approach based on the incidence of grade 3-5 NCI Common Terminology Criteria for Adverse Events (NCI-CTC-AE ) toxicity and / or termination of …
- 0 views
- 16 Feb, 2024
- 1 location
Study to Assess Safety Tolerability Efficacy of PM01183 and Atezolizumab in Patients w/ Advanced Small Cell Lung Cancer.
Prospective, open-label, uncontrolled and multicenter phase I-II study in SCLC patients with ECOG PS 0-1 who have failed one prior platinum-containing line but no more than one chemotherapy-containing line. The study will be divided into two parts: a dose-ranging phase I with escalating doses of PM01183 in combination with a …
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- 16 Feb, 2024
- 5 locations
ADME Study of Acoziborole in Healthy Subjects
All subjects will receive an oral dose of 960 mg [14C] acoziborole on a single occasion as 4 capsules containing a small amount of radioactivity (not more than [NMT] 1000 nCi [37 KBq] 14C).
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- 16 Feb, 2024
- 1 location
AAV Gene Therapy Study for Subjects With PKU
Participants will receive a single administration of BMN 307 and will be followed for safety and efficacy.
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- 16 Feb, 2024
- 1 location