a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 2490 clinical trials
Study to Investigate the Receptor Occupancy of HTL0014242 Using [18F] FPEB in Healthy Male Subjects

A Study in Healthy Volunteers to Investigate How a New Drug for the Treatment of Parkinson's Disease, Dystonia and Amyotrophic Lateral Sclerosis Binds to Receptor Sites in the Brain.

electrocardiogram
  • 0 views
  • 16 Feb, 2024
  • 1 location
Reduction of COVID 19 Transmission to Health Care Professionals

A patient of group "O" would thus defend himself much better against a virus carrying antigens of blood group "A", the natural antibodies "anti-A" of the patient reducing the ability of the virus to bind to its specific receptor on pulmonary epithelial cells, to penetrate them to replicate itself.

epithelial cells
  • 0 views
  • 16 Feb, 2024
  • 1 location
Investigation of New Intermittent Catheters in Healthy Volunteers

Investigation of non-CE marked intermittent catheters. The study is a randomized, single blinded, cross-over investigation comparing two new catheters with a comparator catheter in 30 adult healthy volunteers.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Immunological Biomarkers in Tuberculosis Management

Investigators propose to evaluate the performance in terms of diagnosis accuracy and outcome prediction of four new biomarkers of active TB: 1) a double IGRA (Interferon Gamma Release Assay) including QuantiFERON-Gold Plus and HBHA; 2) a whole blood transcriptomic analysis of mRNA (messenger Ribonucleic acid) expression of a panel of …

immunophenotyping
interferon
curb
latent tuberculosis
interferon-gamma release assay
  • 0 views
  • 16 Feb, 2024
  • 1 location
Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration

This study will evaluate which procedure is the best for patients referred for biopsy of a lung nodule (growth in the lung) meeting the size and location requirements of the protocol. Two different procedures are available for lung nodule biopsy: a computed tomography guided biopsy ("CT-guided biopsy") which consists of …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Teaching Novel Values-Based Skills to Improve Long-Term Weight Loss

This NIDDK funded R01 project is a randomized controlled clinical trial to compare the efficacy of an intervention based on Acceptance and Commitment Therapy (ACT) and a Self-Regulation (SR) intervention on weight loss maintenance over a 30-month period.

body mass index
acceptance and commitment therapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Nivolumab in Combination With Temozolomide and Radiotherapy in Children and Adolescents With Newly Diagnosed High-grade Glioma

Multicenter, open label, prospective study including successively a phase I trial and then a phase II trial Phase I : Open label, non-randomized, safety run study in nine patients. In case of safety issue a -1 dose level will be tested.

malignant glioma
renal function
diffuse glioma
nivolumab
screening procedures
  • 0 views
  • 16 Feb, 2024
  • 1 location
Naproxen Pharmacogenetic Study (Project 1 Aim 2)

CYP2C9 activity will be evaluated by measurement of O-desmethyl naproxen and unchanged naproxen in 24-hour urine following administration of a single oral dose of naproxen (Aleve) in Yup'ik Alaska Native adult men and women who were previously determined in a separate observational study to be homozygous for the CYP2C9*1 allele …

  • 0 views
  • 16 Feb, 2024
  • 1 location
TTNS Versus Sham Therapy for Children With iOAB (TaPaS Part I)

Part I of the TaPaS trial forms part of a twofold clinical RCT: Part 1) A prospective RCT comparing the efficacy of transcutaneous tibial nerve stimulation (TTNS) with TTNS sham therapy for children with idiopathic overactive bladder on clinical and patient reported outcomes (PROMS).

sham therapy
overactive bladder
percutaneous tibial nerve stimulation
incontinence
  • 0 views
  • 16 Feb, 2024
  • 1 location
Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia

This study will evaluate safety, tolerability, and preliminary efficacy of a single intravitreal (IVT) injection of a recombinant adeno-associated virus (AAV) gene therapy, 4D-110, in male patients with genetically-confirmed Choroideremia (CHM).

  • 0 views
  • 05 Aug, 2020