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Found 2 clinical trials
DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolamellar Hepatocellular Carcinoma

The primary objective of the trial is the safety and tolerability of administering a vaccine targeting the DNAJB1-PRKACA fusion kinase, in combination with nivolumab and ipilimumab in patients with unresectable or metastatic FLC and to assess the T-cell response.

core needle biopsy
nivolumab
hepatocellular carcinoma
cancer
carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

The purpose of this project is to realize a randomized open-label study (EudraCT number: 2020-000120-19) to evaluate the safety and the anti-tumor activity of peptide(s)-based immunotherapy in an umbrella window pre-operative opportunity phase II study in patients with squamous cell carcinoma of the head and neck.

platelet count
carcinoma in situ of cervix
cavity
carcinoma in situ of the cervix
neutrophil count
  • 0 views
  • 16 Feb, 2024
  • 1 location