Found 23 clinical trials
Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis
This is a prospective single-center study aiming to build accurate analytical models of MCG to detect coronary lesions and myocardial necrosis. Coronary lesions are measured by coronary angiography (CAG) or coronary CTA, and are defined by both the stenosis degree and the computer-simulated fraction flow reserve. Myocardial necrosis is examined …
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- 10 Nov, 2025
Morphological Parameters of In-stent RESTenosis Assessed and Identified by OCT
OCT during angiography provides a detailed analysis of the stents and potential complications: the presence of neoatherosclerosis with or without plaque rupture, intimal hyperplasia, stent under-deployment, stent fracture and distal or proximal progression of the atherosclerosis.
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- 16 Feb, 2024
- 1 location
Eisai, Inc._E2086-G000-202_140993-01_Narcolepsy (140993-01)
To identify the optimal doses of E2086 compared to placebo in subjects with narcolepsy for reduction of excessive daytime sleepiness (EDS) as assessed by Mean Sleep Latency (MSL)
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- 23 Jun, 2026
Angiography-Derived FFR And IVUS for Clinical Outcomes in Patients With Coronary Artery Disease
Comparison of Angiography-derived Fractional FLow Reserve And IntraVascular Ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with CoRonary Artery Disease
- 2 views
- 05 Aug, 2020
Resting Full-cycle Flow Ratio (RFR) Versus Angiography to Guide Revascularization Strategy in Patients Undergoing Coronary Artery By-pass Grafting (CABG)
It is unknown whether RFR guided CABG revascularization is superior as compared to angiography alone.
- 0 views
- 05 Aug, 2020
Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI
Grading paravalvular leakage after TAVI is difficult. Echocardiography and angiography systematically underestimate paravalvular leakage (PVL) as compared to cardiac MRI. Hemodynamic measurements are used to aid decision making directly after TAVI implantation.
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- 16 Feb, 2024
- 1 location
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication
Prospective, multi-center, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Complex Abdominal Aortic Aneurysms.
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- 16 Feb, 2024
- 3 locations
Impact of Mitral Regurgitation on Coronary Haemodynamics and Instantaneous Effect of Transcatheter Mitral Valve Repair
In the present study, the investigators aim to use the in-vivo Transcatheter Mitral Valve Repair (TMVR) model to determine how Mitral Regurgitation (MR) affects coronary hemodynamics in patients affected with severe MR and concomittant angiographically-documented coronary artery disease. The investigators will also provide unique physiologic data on the acute effect …
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- 16 Feb, 2024
- 1 location
Heart Attack Blood Oxygen Therapy Trial (SSO2 Radial MI)
'Heart attack', known as acute ST-segment elevation myocardial infarction, is a leading cause of heart failure and death. A lack of blood and oxygen damages the heart muscle potentially causing heart failure and premature death.During the past 25 years, despite intensive research efforts, few, if any new medicines have been …
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- 12 Sep, 2025
Invasive Coronary Angiography Early in Ischemic Heart Failure
To compare the outcomes of patients with acute heart failure who undergo early coronary angiography vs. usual care
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- 16 Feb, 2024
- 1 location