Found 1697 clinical trials
A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS.
Patients who continue to be benefit after 6 cycles' treatment will receive additional cycles of treatment until progression of disease, unacceptable toxicity is observed or administrative discontinuation. (As long as it is proven safe).
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- 16 Feb, 2024
- 1 location
![A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants](/media/imagery/10642.svg)
A Study of the Biodistribution and Safety of [18F]GTP1 in Healthy Japanese Participants
The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants.
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- 05 Aug, 2020
Vestibular Nerve Stimulation to Improve Sleep
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS) compared to a sham control a as a means of improving sleep as measured by ISI scores and EEG recordings The purpose of this investigation device study is to collect data that will …
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- 16 Feb, 2024
- 1 location
Left Atrial Posterior Wall Additional Isolation for Persistent Atrial Fibrillation Trial
The purpose for this study is to determine whether left posterior wall isolation (PWI) in addition to pulmonary vein isolation (PVI) is effective as ablation strategy for persistent atrial fibrillation (AF).
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- 16 Feb, 2024
- 1 location
A Study of Sintilimab Combined With Apatinib and Capecitabine in Advanced Hepatocellular Carcinoma
This study aims to evaluate the efficacy and safety of Sintilimab (an Anti-PD-1 Inhibitor) combined with apatinib and capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma.
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- 16 Feb, 2024
- 1 location
Radiomics Tool for Pulmonary Nodule Risk Stratification
Final pulmonary nodule diagnosis will be categorized as malignant or benign. If the pathology report does not offer a specific pathologic diagnosis or is inconclusive (i.e., the biopsy was non-diagnostic), we will define pulmonary nodule resolution, shrinkage, or diameter stability at 12 months as a benign diagnosis.
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- 11 Jul, 2024
- 1 location
Treatment of Critically Ill Patients With Covid-19 With Convalescent Plasma
This study aims to collect convalescent plasma and use it as experimental treatment in critically ill Covid-19 patients in order to reduce mortality and length of stay in intensive care unit.
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- 05 Aug, 2020
Tofacitinib for Immune Skin Conditions in Down Syndrome
Investigators will also measure the impact of interferon inhibition on a variety of molecular markers, as well as the cognitive abilities and quality of life of participants.
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- 16 Feb, 2024
- 1 location
Suicide Prevention for Patients With Chronic Pain
We have used an adaptive design so that if there is strong evidence for target engagement, we will continue with the trial as a fully powered clinical trial (i.e., the end of the current proposal will act as the interim assessment) to the determine the efficacy of remote PST for …
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- 16 Feb, 2024
- 1 location
Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture
The objective of this trial will be to establish whether the ultrasound-guided suprainguinal fascia iliaca compartment block is capable of protecting geriatric patients with hip fracture from delirium as compared to placebo
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- 16 Feb, 2024
- 1 location