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Found 1431 clinical trials
Safety and Preliminary Efficacy of Combination Therapy for the Treatment of Acne Vulgaris  

Use of MCT alone or in combination with current successful treatment such as blue light phototherapy (BLP), may hold promise for acne treatment

  • 0 views
  • 06 Oct, 2023
  • 1 location
Respiratory Muscle Training (RMT) in ALS

Participants will be stratified into 2 groups based on baseline inspiratory muscle strength as determined by maximum inspiratory pressure (MIP): six participants with minimal to no respiratory weakness (i.e., MIP 70% predicted) and six participants with mild to moderate inspiratory weakness (i.e., MIP 40-70% predicted).

maximum inspiratory pressure
maximum expiratory pressure
respiratory muscle training
weakness
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Effect of a Low FODMAP Diet in Irritable Bowel Syndrome Patients

Tertiary care IBS patients will be recruited for a prospective low FODMAP intervention study, hereby focusing on the reintroduction phase of the diet, where patients are blindly challenged with different FODMAP groups administered as powder, to be added to the strict FODMAP exclusion phase. During the screening phase of two …

fodmap diet
irritable bowel syndrome
  • 0 views
  • 16 Feb, 2024
  • 1 location
The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

This application can disrupt tissue oxygenation due to both Operation position and single lung ventilation. Thoracic epidural analgesia, which is applied as the gold standard of Thoracic Surgery, is applied prior to the operation and is provided to assist in postoperative analgesia.

analgesia
single lung ventilation
probe
thoracic surgery
lung ventilation
  • 0 views
  • 16 Feb, 2024
  • 1 location
18F-DCFPyL PET/CT Impact on Treatment Strategies for Patients With Prostate Cancer

The scan will be used to see how the disease has spread. Both the treatment strategies and probable disease outcomes as relevant to clinical endpoints will be assessed. This study is open to Veterans only.

definitive treatment
ct scan
prostate cancer metastatic
conventional imaging
pet/ct scan
  • 0 views
  • 05 Aug, 2020
Helping Families Pilot of a Family Resilience Program for Families Experiencing Homelessness and Parental Substance Use

For the families assigned to the treatment as usual group, they will continue to receive case management services from their residential facilities. Families in both groups will be asked to fill out 3 surveys (one at the beginning of the program, one at the end of the program, and at …

  • 0 views
  • 16 Feb, 2024
  • 1 location
The Young Heart Study

The purpose of our project is to better understand the characteristics of the young patients with coronary artery disease presenting for cardiac catheterization at our institution and to put forth a program to optimize their risk factors with a focus on gender differences. We will assess traditional and non-traditional risk …

arterial disease
cardiovascular disease
atherosclerosis
coronary disease
anxiety
  • 0 views
  • 16 Feb, 2024
  • 1 location
Feasibility and Effectiveness of Delivering Cognitive Behaviour Therapy Through Online Psychotherapy Tool (OPTT) for Depression

This study also aims to determine the difference in efficacy between e-CBT alone, pharmacotherapy alone and e-CBT with pharmacotherapy as it relates to various demographic characteristics (i.e., gender, age, socioeconomic status, etc.). To the principal investigators' knowledge, this study will be the first multi-site study examining the efficacy of e-CBT …

depressive disorder
major depressive disorder
psychiatric disorder
cognitive therapy
anxiety
  • 0 views
  • 16 Feb, 2024
  • 1 location
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as lenalidomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them …

stage iv grade 1 follicular lymphoma
grade 3 follicular lymphoma
bone marrow procedure
prothrombin
ct scan
  • 0 views
  • 16 Feb, 2024
  • 1 location
Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)

The primary hypothesis is that pembrolizumab + lenvatinib is superior to SOC chemotherapy with respect to ORR per modified Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 as assessed by blinded independent central review.

paclitaxel
squamous cell carcinoma
mk-3475
contraceptive use
cavity
  • 0 views
  • 16 Feb, 2024
  • 3 locations