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Found 6007 clinical trials
Anticoagulation in Emergency General Surgery

While DOACs are increasing in use in the EGS patient population, the risk of bleeding and the reversal of these agents to reduce hemorrhage is still evolving. Given the paucity of data regarding the impact of DOACs in this patient population, it becomes empiric to identify bleeding patterns and outcomes …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Chronic Obstructive Pulmonary Disease (COPD) and Advance Directives

The aim of this study is to evaluate if the participation of COPD patients to a workshop on advance directives increases the number of patients who write them.

pulmonary disease
lung disorder
  • 0 views
  • 16 Feb, 2024
  • 1 location
Gene Mutation Spectrum of Malignant Hyperthermia in China

In this study, case information and specimens of patients with malignant hyperthermia(MH) will be collected from all over China, and gene fragment analysis, sanger sequencing method and/or high-throughput whole-genome sequencing will be performed. The MH bioinformatics database will be established to find the pathogenic gene and mutation site of MH …

  • 0 views
  • 05 Aug, 2020
Population at Risk of Malignant Hyperthermia: Ambispective Cohort.

Malignant hyperthermia (MH) is a pharmacogenetic disease that manifests itself as a hypermetabolic response of skeletal musculature, in genetically susceptible patients, with the inhalation of volatile halogenated anesthetics, depolarizing neuromuscular relaxants such and, rarely, physical stressors such as intense exercise and heat stroke. HM diagnosis is based on the performance …

  • 0 views
  • 16 Feb, 2024
  • 1 location
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study) (EXE-T1D)  

Type 1 diabetes (T1D) results from destruction of insulin-producing beta cells in the pancreas by the body's own immune system (autoimmunity). It is not fully understood what causes this type of diabetes and why there is variation in age of onset and severity between people who develop the disease. The …

  • 0 views
  • 04 Jul, 2023
  • 3 locations
A Multidisciplinary Outpatient Pathway

Patients with complex chronic multiple illnesses constitute an increasing challenge and more evidence-based knowledge of effective practice is required. In Denmark and the rest of the world, improved health care, public health, and increased focus on early diagnosis have led to increases in life expectancy resulting in a growing population …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Cardio-Oncology Registry

CONFUCIUS is a single tertiary centre prospective registry including all patients who have been referred for cardio-oncology assessemnt. The objectives are to provide a comprehensive vue of cardoi-oncology, enable to detect early signals of cardiotoxicity and enhance ancillary projetcts aiming at specific populations (e.g., type of cancer) and/or drugs.

cancer
cardiotoxicity
  • 0 views
  • 16 Feb, 2024
  • 1 location
Therapeutic Recommendations for Nephroblastoma

The study is based on results form 2 previous studies carried out by the GFAOP. The aim of this study is to evaluate the capacity of units to follow the recommendations in the protocol.

wilms' tumour / nephroblastoma
  • 0 views
  • 05 Aug, 2020
Cell-free DNA in Hereditary And High-Risk Malignancies

The goal of this study is to develop an effective, sensitive blood test that can detect early tumours in patients with known or suspected hereditary cancer syndromes (HCS). If this new blood test is accurate, it could be used to screen patients for cancer and allow for earlier cancer detection.

blood test
cancer
cell-free dna
hereditary cancer
hereditary cancer syndromes
  • 0 views
  • 16 Feb, 2024
  • 7 locations
Duke Spine Outcome Study (DSOS)

The study will require obtaining spinal lesions (tumor, etc.), blood, and bone marrow samples (from non-lesional bone) from selected patients, which will be collected during your surgery.

spinal disease
cancer diagnosis
spine surgery
neurosurgery
metastatic disease
  • 0 views
  • 16 Feb, 2024
  • 1 location