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Found 6007 clinical trials
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts the body and is PD-L1-negative. The names of the study interventions involved in this study are: Sacituzumab govitecan (IMMU-132) Pembrolizumab (Keytruda; MK-3475)

central nervous system disease
breast cancer
sacituzumab govitecan
brain metastases
HER2
  • 8 views
  • 05 Aug, 2020
CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

Drugs used in chemotherapy, such as CPX-351, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

ejection fraction
myelodysplasia
chronic myelomonocytic leukemia
treatment related acute myeloid leukemia
plasma creatinine
  • 0 views
  • 16 Feb, 2024
  • 1 location
Ibrutinib + Venetoclax in Untreated WM

This study evaluates the safety and efficacy of Ibrutinib combined with Venetoclax (IVEN) in the treatment of adults diagnosed with Waldenstrom's macroglobulinemia (WM) cancer with a specific MYD88 gene mutation. This research study involves an experimental drug combination of targeted therapies.

growth factor
bone marrow biopsy
absolute neutrophil count
venetoclax
platelet transfusion
  • 0 views
  • 16 Feb, 2024
  • 2 locations
  • 0 views
  • 06 Dec, 2023
  • 2 locations
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  • 0 views
  • 28 Sep, 2023
  • 1 location
  • 0 views
  • 18 Dec, 2023
  • 1 location
A Daily-Activity-Focused, Strategy-Based Educational Programme for Informal Dementia Carers

This study will assess the impact of the Dementia Carer Education Programme on the caregiving burden of informal dementia carers.Ninety informal dementia carers along with their care-recipients will be recruited and randomised to the experimental and control groups. All recruited dementia carers in the experimental group will receive the Dementia …

  • 0 views
  • 16 Jun, 2025
Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma

This is a phase III randomized clinical trial of definitive radiotherapy plus EGFR blocker nimotuzumab versus radiotherapy plus cisplatin(CCRT) for nasopharyngeal carcinoma (NPC) patients with favorable response to induction chemotheray(IC), determining whether radiotherapy combined with nimotuzumab was non-inferior to CCRT and may provide new evidence for individualized comprehensive treatment of …

nasopharyngeal carcinoma
epstein-barr virus dna
carcinoma
EGFR
renal function test
  • 0 views
  • 16 Feb, 2024
  • 1 location
Pembrolizumab Plus Paclitaxel Cisplatin Followed by Surgery for Locally Advanced ESCC

The purpose of this study is to observe and evaluate the efficacy and safety of pembrolizumab plus paclitaxel, cisplatin followed by Da Vinci robot radical surgery for locally advanced esophageal squamous cell carcinoma.

pembrolizumab injection
carcinoma
squamous cell carcinoma of esophagus
paclitaxel
squamous cell carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

nasopharyngeal carcinoma
chemoradiotherapy
carcinoma
concurrent radiochemotherapy
karnofsky performance status
  • 0 views
  • 16 Feb, 2024
  • 1 location