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Found 505 clinical trials
Effect of Minocycline on Delirium Incidence in Critically Ill Patients

Delirium will be diagnosed by the CAM-ICU. Coma will be defined by the Richmond Agitation-Sedation Scale (RASS) score of -4 or -5 and biomarkers will be used as alternative outcomes related to the pathophysiology of the disease (IL-1, IL-6, IL-10, and BDNF).

bdnf
antipsychotics
agitation
il-6
mechanical ventilation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cognitive Behavioral Therapy for Insomnia for the Dementia Caregiving Dyad

Disturbed sleep is stressful to persons living with dementia (PLwD) and their caregivers. It contributes to earlier placement of the PLwD in nursing homes and increase the risk for many psychological and cognitive health issues and poor quality of life for both the PLwD and the caregivers. Given the potential …

actigraphy
hearing impairment
psychotropic drugs
alzheimer's disease
sleep disorder
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Myocardial Contrast Echocardiography in Septic Patients

Myocardial microcirculatory alterations may be involved in the pathogenesis of acute cardiac dysfunction or septic cardiomyopathy in septic patients. The investigators study the cardiac function (systolic and diastolic) with two-dimensional echocardiography (TTE), and the myocardial microcirculation with contrast echocardiography (MCE) and sulphur hexafluoride microbubbles Sonovue injection in ICU septic patients.

cardiomyopathy
shock
lactate level
resuscitation
septicemia
  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical Features Associated With Restless Legs Syndrome.

Restless legs syndrome (RLS) is a chronic neurological disorder characterized by an urge to move the legs at night when at rest. RLS can lead to a sleep deprivation, increased falling risk, daytime sleepiness, depression and decreased quality of life.

sleepiness
dopamine agonists
restless legs syndrome
depression
neurological disorder
  • 0 views
  • 15 Sep, 2021
  • 1 location
The Effect of Pediatric Patient Temperament on Postoperative Outcomes

These data will be used to determine if patients with a specific temperament profile are more likely to experience increased pain, emergence agitation, emotional changes, and behavioral disturbances postoperatively.

pediatric
agitation
behavioral disturbances
pain assessment
postoperative pain
  • 0 views
  • 16 Feb, 2024
  • 1 location