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Found 3,739 clinical trials

K Kajohnsak Noppakun, MD

Furosemide Stress Test for the Prediction of Acute Kidney Injury Severity in Acute Heart Failure Patients

This study is aim to study the changes of serum creatinine levels at 72 hours after admission in patients with acute heart failure who has diuretic resistance compared to those who do not have diuretic resistance from furosemide stress test

18 years and older All Phase N/A
D Dirk Johannes Schaefer, Prof. Dr. med.

Patient Reported Outcome Measures After Treatment of Skin Cancers on the Face

This study is to evaluate the psychological well-being in patients diagnosed with skin cancer (melanoma and Squamous Cell Carcinoma (SCC) in the face) at the time of diagnosis and after treatment. Patients diagnosed with primary melanoma and/or SCC and/or infiltrative basal cell carcinoma on the face subjected to surgical treatment …

18 years and older All Phase N/A
L Laura Rudeen

Observational Post Market Study in Treating Chronic Upper Extremity Limb Pain

This is a post-market, open-label, prospective, multi-center, observational study evaluating upper limb pain relief with the DTM SCS programming approach. Data at follow-up visits will be compared to baseline assessments collected at the beginning of the study.

18 years and older All Phase N/A
M Max Ettinger, PD Dr.

Kinematic Versus Mechanical Alignment in Total Knee Replacement

This prospective controlled double-blind randomized study compares kinematic and mechanical alignment in TKA (Total knee arthroplasty). A total of 120 patients will be included and the surgery will be performed using CT based 3D printed PSI(Patient Specific Instruments) Cutting guides.

18 years and older All Phase N/A
E Erin Watters

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

Use of indocyanine green will augment the accuracy of identification and resection of both primary solid malignancies as well as their pulmonary metastases, where applicable We will conduct a prospective feasibility study of pediatric patients with solid malignancies with or without lung metastatases who present at the time of initial …

45 years and younger All Phase N/A
R Robert Lewandowski, MD

Optimizing Y90 Therapy for Radiation Lobectomy

HCC resection candidates with inadequate future liver remnant will be enrolled in this study. They will be treated with Y90 radioembolization to help grow the liver enough to undergo liver resection. There will be 2 Patient Groups. The first group of patients will be treated with Y90 dose and embolic …

18 years and older All Phase N/A
B Barbara (BJ) Thomas, R.N.

Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

Background Neuroendocrine neoplasms (NENs) are rare tumors that originate in neuroendocrine cells. NENs can affect almost any part of the body. People with low-grade tumors can live many years. But high-grade tumors can be very aggressive. Researchers want to learn more about this type of cancer. This may help them …

3 years and older All Phase N/A
C Christoph Germann, MD

High-resolution 7 Tesla MRI of C-spine - Comparison With 3 Tesla MRI

High-resolution MRI (7 Tesla) of the cervical spine is capable to differentiate osseous spurs from discus-material and better depict the compressed nerve in the neuroforamen compared to 3T MRI. Provide the surgeon with a detailed high-resolution anatomical image before surgery and potential no need for CT (if the bony anatomy …

18 years and older All Phase N/A
A Andreas Andersen

Glycaemia and Cardiac Function in Patients With COVID-19

The study design is observational, exploratory study consisting of two cohorts of COVID-19 patients admitted to the ICU and the medical ward, respectively. The primary outcome focusing on the effect of plasma glucose levels on cardiac function will be evaluated by repeated assessment of cardiac function by echocardiography and measurement …

18 years and older All Phase N/A
W Walter Swardfager, PhD

The Sunnybrook Type 2 Diabetes Study

The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from …

18 years and older All Phase N/A

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