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Found 36801 clinical trials
A Patient-centered Continuous and Interdisciplinary Shared Decision Making Approach for Breast Cancer Rehabilitation

Background: Breast cancer rehabilitation has gradually expanded from post-surgery rehabilitation to continuous rehabilitation including prehabilitation between cancer diagnosis and surgical treatment, post-surgery rehabilitation, and return-to-work/return-home interventions.

  • 0 views
  • 16 Feb, 2024
  • 1 location
A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab

Moreover, the study will characterize the pharmacokinetic profiles of NIZ985 as a single agent and in combination with Spartalizumab and identify preliminary anti-tumor activity.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Combined Locoregional Treatment With Immunotherapy for Unresectable HCC.

Efficacy and Safety of Locoregional treatments Combined With PD-1 Inhibitor in Patients With Unresectable Hepatocellular Carcinoma.

microwave ablation
TACE
unresectable hepatocellular carcinoma
carcinoma
hepatocellular carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of CN1

This study is the first-in-human clinical trial of CN1 to evaluate the safety, tolerability, pharmacokinetic (PK) profile and preliminary efficacy of CN1 in patients with advanced solid tumors or B-cell lymphoma. This study will provide a basis for further clinical development of CN1.

lymphoma
b-cell lymphoma
solid tumour
  • 0 views
  • 16 Feb, 2024
  • 1 location
Safety of Minimally Invasive Surgery Using Endoscopic Stapler in Early Stage Cervical Cancer Patients (SOLUTION)

The SOLUTION trial aims to show the efficacy and safety of performing radical hysterectomy by minimally invasive surgery using an endoscopic stapler in patients with cervical cancer stage IB1 (FIGO staging 2009) and thus to prove that minimally invasive surgery is non-inferior to open surgery.

cervical disease
hysterectomy
cervical carcinoma
minimally invasive surgery
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer

This is a randomised, double-blinded, placebo-controlled, multi-center phase III trial, comparing the efficacy and safety of treatment with Camrelizumab (SHR-1210) + definitive chemoradiotherapy(dCRT) vs placebo+dCRT for locally advanced esophageal cancer patients in China. Camrelizumab (SHR-1210) is a humanized anti-PD1 IgG4 monoclonal antibody.

chemoradiotherapy
monoclonal antibodies
squamous cell carcinoma of esophagus
camrelizumab
antibody therapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

All patients enrolled in the study will receive infusion of MTX110 and Gadolinium delivered with a pump directly into the tumor over 9-11 days.

acute infection
epilepsy
serum pregnancy test
neutrophil count
side effects of drugs
  • 0 views
  • 16 Feb, 2024
  • 1 location
Preliminary Antitumor Activity Safety and Tolerability of Tislelizumab in Combination With Lenvatinib for Hepatocellular Carcinoma

The primary objective of this study is to assess the preliminary antitumor activity as indicated by overall response rate (ORR) of tislelizumab in combination with lenvatinib in participants with unresectable locally advanced or metastatic hepatocellular carcinoma (HCC).

unresectable hepatocellular carcinoma
lenvatinib
hepatocellular carcinoma
metastatic hepatocellular carcinoma
cholangiocarcinoma
  • 0 views
  • 05 Aug, 2020
Food Supplements Based on Nettle and Peppermint to Control Signs and Symptoms Induced by Cancer Therapies

The main purpose of this study is to evaluate the impact of food supplements (herbal remedies) on sign and symptoms induced by cancer therapies: Nettle will be administered for improvement of anemia and fatigue; Peppermint will be administered for improvement of nausea.

inhibitors, parp
parp inhibitor
stinging nettle
cancer therapy
adjuvant
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy

Endocrine therapy is the initial treatment for most hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancers. This study will evaluate the use of venetoclax in combination with capecitabine in adult participants with HR+, HER2-, metastatic breast cancer (MBC) who had disease progression following treatment …

capecitabine tablets
venetoclax
erbb2
epidermal growth factor
stage iv breast cancer
  • 0 views
  • 16 Feb, 2024
  • 16 locations