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Found 3,739 clinical trials

S Sean Harrison

Early Diagnosis of Upper Digestive Tract Disease

Upper digestive tract cancer (UDC) is a major disease burden worldwide encompassing all cancers involving the digestive tract (from oral cavity to duodenum). A majority of patients presenting with this disease are diagnosed late and have poor overall survival rates (<20%). NICE referral guidelines for diagnostic endoscopy are usually associated …

18-90 years All Phase N/A
J Jaime Altcheh, Phd MD

Acquired Syphlis by Non Sexual Contact

Syphilis is classically described as a sexually transmitted disease. As this source of contagious has been described long ago -mainly though by observation- when children presents with acquired syphilis, child abuse is always considered and must be ruled out by specialists in a careful evaluation. However, muco-cutaneous lesions can be …

18 years and younger All Phase N/A
C CHANQUES Gerald, MD

Evaluation of the Satisfaction of Patients Coming "on Foot" in the Operating Room

Ambulatory surgery is currently experiencing unprecedented growth and is becoming the standard of care compared to traditional hospitalization. Without mentioning the obvious financial gains, the benefits of ambulatory care essentially lie in optimised perioperative comfort. This comfort is due to a limited period of stay (< 12 hours) and to …

18 years and older All Phase N/A
J Justice Quame-Amaglo

Streamlining the Efficiency of PrEP Implementation

This is a pilot facility-based direct-to-pharmacy PrEP refill delivery to streamline care pathway in Kenyan public health HIV facilities implementing PrEP. Data on up to 500 PrEP users will be evaluated to understand delivery efficiency and in-depth interview with users and delivery key informants will be conducted to identify barriers …

18 years and older All Phase N/A
T Thomas Lenarz, Prof. Prof. h.c. Dr.

The BCI 602 BONEBRIDGE Post-Market Clinical Follow-up Study

The Bonebridge system using the BCI 601 is marketed since 2012. Previous prospective, multi-center, non-randomized studies on the BCI 601 Bonebridge performed in adult and paediatric populations have shown a significant improvement in terms of aided sound field (SF) thresholds, word recognition scores (WRS), speech reception thresholds (SRT) and subjective …

5 years and older All Phase N/A
M Mary E Patti, MD

Mechanisms of Hypoglycemia in Patients Without Diabetes

The goal of this study is to identify physiologic and molecular mechanisms that underlie hypoglycemia in the absence of diabetes (or medications that can cause hypoglycemia) and to investigate potential genetic and microbiome differences which contribute to hypoglycemia. We will test the hypothesis that hypoglycemia in the absence of diabetes …

18-70 years All Phase N/A
L Lori McGee Koch

Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms

Develop a wearable sensor package to gather data on COVID-19-like signs and symptoms such as elevated body temperature, respiratory parameters, heart rate ,cough and gait. Create algorithms to monitor and track changes to COVID19-like signs and symptoms for developing a better care and isolation strategies for COVID-19 pandemic.

18-95 years All Phase N/A
d davidrussell-jones@nhs.net, PhD

Use of Dexcom G6 in Commercial Pilots With Insulin Treated Diabetes

The investigators wish to explore the use of the CGMS Dexcom G6 in pilots with insulin-treated diabetes, who are flying commercial aircraft with Class 1 and flying instructors or private pilots with class 2 certificates. The aim of this study is to explore the severity and number of hypoglycaemic episodes …

18-75 years All Phase N/A
M Mehmet K Kanburoglu, M.D.

Characteristics of Neonatal Covid-19 in Turkey

The investigators aimed to investigate the clinical and epidemiological characteristics of neonates who will be born to Covid-19 positive mothers in Turkey. It is a multicentric prospective cohort study designed and destined only in Turkey. The investigators are planning to admit more than 20 Neonatal Intensive Care Units into the …

1 years and younger All Phase N/A
M Miguel Ayala León, MD

Echocardiographic Assessment of Ventricular Strain During a Healthy Pregnancy in the First Second and Third Trimester.

Pregnancy is a physiological situation that produces transient preload and afterload changes. The heart is subjected to reversible morphological remodelings and hemodynamic and functional adaptations. The characterization and understanding of maternal cardiac function during normal pregnancy by echocardiography 2D is of clinical importance for the opportune recognition of cardiac pathology. …

20-35 years Female Phase N/A

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