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Found 36801 clinical trials
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

screening procedures
gonadotropin
alopecia
stage iv breast cancer
solid tumor
  • 0 views
  • 16 Feb, 2024
  • 5 locations
Cemiplimab Before and After Surgery for the Treatment of High Risk Cutaneous Squamous Cell Cancer

This phase I trial studies how well cemiplimab before and after surgery works in treating patients with high risk cutaneous squamous cell cancer. Immunotherapy with monoclonal antibodies, such as cemiplimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

monoclonal antibodies
international normalized ratio
cancer therapy
neuropathy
hormone replacement therapy
  • 0 views
  • 05 Aug, 2020
A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer

This study will evaluate the safety, tolerability, and pharmacokinetics of BLYG8824A and will make a preliminary assessment of the anti-tumor activity of BLYG8824A in patients with locally advanced or metastatic colorectal cancer.

oxaliplatin
irinotecan
EGFR
antibody therapy
measurable disease
  • 0 views
  • 05 Aug, 2020
Black Raspberry Nectar for the Prevention of Lung Cancer BE WELL Study

This trial studies how well black raspberry nectar works in changing the gut microbiome and in reducing inflammatory processes that may lead to lung cancer. Studying the effects of black raspberry beverage on inflammation may help doctors find strategies to reduce the risk of developing lung cancer.

lung cancer
cancer
carcinoma
lung carcinoma
vitamins
  • 0 views
  • 16 Feb, 2024
  • 1 location
Pembrolizumab Plus Pemetrexed for Elderly Patients With Non-Sq NSCLC With PD-L1 < 50%: CJLSG1901

To evaluate the efficacy and safety of Pembrolizumab + Pemetrexed in elderly patients with non-squamous non-small cell lung cancer with Programmed cell death (PD) -ligand1 (L1) tumor proportion score (TPS) of less than 50%.

pembrolizumab
EGFR
adjuvant
recurrent non-small cell lung cancer
small cell lung cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
test cancer 54321

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  • 0 views
  • 20 Feb, 2026
  • 1 location
Intra-gastric Fundal and Body Injection of Botulinum Toxin A for Weight Loss a Randomized Controlled Trial

This is a randomized controlled trial to compare intra-gastric injection of Botulinum Toxin A (Botox; Allergan Inc. Irvine, Ca, USA) against non-surgical management for obesity (i.e. exercise/diet). Our hypothesis is that intra-gastric injection of Botox into the fundus and body of the stomach will result in greater weight loss than …

botulinum toxin type a
botox
injection of botulinum toxin
botulinum toxin
weight control
  • 0 views
  • 16 Feb, 2024
  • 1 location
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs

The investigators are doing this study to find out whether lowering the dose of postoperative radiation therapy and targeting a smaller area of tissue for treatment is as effective as the standard dose and volume of radiation therapy to control soft tissue sarcoma after surgery. They also want to find …

sarcoma
primary tumor
soft tissue sarcoma
serum pregnancy test
sarcoma of the extremity
  • 0 views
  • 16 Feb, 2024
  • 7 locations
Establishment of a Prospective Clinical-biological Database

A Clinical and Biological Database will provide to the scientific community a collection of blood and tissues with clinical data to improve knowledge about cancer and help to develope new cancer treatments. This database is specific to Sarcoma

sarcoma
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
Platinum-Based Chemotherapy and Durvalumab for the Treatment of Stage IIIB or IV Non-small Cell Lung Cancer

Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The purpose of this study is to find out if the combination of chemotherapy in combination with the immune therapy drug …

non-small cell carcinoma
drug test
cancer therapy
hormone replacement therapy
granulomatosis
  • 0 views
  • 16 Feb, 2024
  • 2 locations