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Found 3,739 clinical trials

V Volker Rudolph, Prof.

MiCLASP Post Market Clinical Follow-Up (PMCF) Study

This is a postmarket clinical follow up study on the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in transcatheter mitral valve repair.

18 years and older All Phase N/A
C CEO

Recognition of Heart Failure With Micro Electro-Mechanical Sensors (REFLECS) FI

Heart Failure (HF) is a condition where heart is unable to maintain adequate volume of blood in circulation corresponding to prevailing physiological demand. Gyrocardiography is a technique that utilizes micro electromechanical sensors (MEMS), accelerometer and gyroscope, to detect vibrations and rotation of thorax caused by cardiac motion. The main purpose …

18 years and older All Phase N/A
X Xavier DUFOUR, Pr

Prevalence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Following Squamous Cell Carcinomas of the Oropharynx Treatment by Combined Chemoradiotherapy

The study's aim is to determinate the prevalence of obstructive sleep apnea hypopnea syndrome after treatment by combined chemoradiotherapy in a locally advanced stages treated population of oropharyngeal cancer. Indeed, the level of knowledge about the consequences of oropharyngeal cancer treatment on sleep quality remains poor but the few studies …

18 years and older All Phase N/A
C Charis Sugden

Observational Study to Assess Transradial Access for Treatment in the Lower Extremities.

This study is designed to collect data on the complication rates and procedural success of using a transradial access approach to treat peripheral lesions in the lower extremities of a real world population.

18 years and older All Phase N/A
F François GIRODON

Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800 an Inhibitor of the Heat Shock Protein HSP90

NVP-BEP800, a new HSP90 inhibitor, has particularly interesting therapeutic potential and represents hope in cancer pathologies. While it is currently being tested for solid cancers, no preclinical study has yet demonstrated its effectiveness in acute lymphoblastique leukemia (ALL). The investigators wish to study the effects of NVP-BEP800 on two different …

18-80 years All Phase N/A
H Harry Magunia, MD

Echocardiography in Patients With Covid-19

Prospective observational study of patients treated due to Covid-19 disease. Observation and analysis of echocardiographic studies performed in the intensive care setting.

18 years and older All Phase N/A
B Benjamin Misselwitz, Prof.

Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Background: Intestinal microbiota composition is fundamental to human health and undergoes critical changes within the first two years of life. Factors probably influencing the microbiota are the maternal microbiota and the general environment in Switzerland. However, the development of the intestinal microbiota is incompletely understood. Gaining knowledge of the trajectory …

18-45 years Female Phase N/A
J José Carlos Nicolau

Effect of COVID-19 on Platelet Aggregation

This is a mechanistic, observational, prospective, case and control study, to compare platelet aggregation, analyzed by Multiplate-ADP, in hospitalized patients diagnosed with COVID-19 versus healthy controls. Thus will be included 50 patients who present with respiratory symptoms within 72 hours of hospitalization and confirmation of the diagnosis of COVID-19 by …

18 years and older All Phase N/A
E Ebtsam MM Tawfik, M.D.

Anxiety and Depression Disorder in Patient Treated With rTPA for Mangment of Acute Ischemic Stroke

In fact theWorld Health Organization estimates that 2-3% in general populations of countries across the world tend to be affected by severe mental disorders (1) Thrombolytic therapy seems to be of great importance in achieving better quality of life in ischemic stroke patients who respond to this therapy(rTPA).

40-75 years All Phase N/A
G Gina Townley

Assessment of Olfactory Dysfunction in SARS CoV-2 (COVID-19) Infection

This study is designed to investigate the acuity of olfactory dysfunction in COVID-19 positive patients in the United Kingdom. In particular defining severity with objective testing and determining if this has any predictive value on the outcome of the SARS CoV-2 infection. In addition, this study will strive to determine …

18-85 years All Phase N/A

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