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Found 3,739 clinical trials

S Si-Yang Liu

The Real World Study of Neoadjuvant Immunotherapy in Early Stage NSCLC in China

Several published clinical trials have shown the superiority of immunotherapy in neoadjuvant setting. Here we conducted this real world study to see whether neoadjuvant immunotherapy would bring MPR and survival benefits in NSCLC, for example, single agent immunotherapy or immunotherapy combination with chemotherapy. Furthermore biomarker analysis would be also performed …

18 years and older All Phase N/A
L Lorenz Kuessel, Dr.

CellAdhesionMolecule EndometriosisRatio - CAMERA

Background: Endometriosis, which is characterized by the growth of endometrial stroma and glands outside of the uterine cavity, is estimated to occur in 6-10% of women of reproductive age. Clinical presentation of endometriosis can vary widely, often significantly reducing quality of life, and the mean interval between the onset of …

18-50 years Female Phase N/A
C Charlotte Haslund, M.D

Cerebral Morbidity After Radiation Therapy for Brain Tumors

This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.

18 years and older All Phase N/A
P Per Skoog, MD, PhD

Myocardial Injury in Treatment of AAA

Comparison of elective infrarenal aneurysm surgery with open and endovascular technique, respectively, for subclinical ischemic myocardial injury detectable with troponin T and/or 3-channel Holter ECG with ST analysis

18 years and older All Phase N/A
J Jae-Kwan Song

Evaluation of Prevalence and Clinical Impact of Atrial Fibrillation in Elderly Patients With Cryptogenic Stroke and High-Risk Patent Foramen Ovale

The purpose of DEFENSE-ELDERLY is to identify the prevalence of AF and evaluate the clinical impact of AF in elderly ESUS patients and no other known sources of stroke besides a high-risk patent foramen ovale, and compare it with elderly ESUS patients without high-risk PFO (no PFO or non-high risk …

60 years and older All Phase N/A
M Maija Koivu, M.D.

Comparison of Outcomes in Asleep and Awake DBS With a Directional Electrode

To compare the clinical outcome of patients with Parkinson's disease (PD) treated with directional deep brain (dDBS) stimulation undergoing subthalamic deep brain stimulation operation (STN-DBS) under general anesthesia versus local anesthesia.

80 years and younger All Phase N/A
J Jørgen Jensen, Professor

Influence of Hormone Treatment in Radiation Therapy for Bladder Cancer

Bladder cancer is often treated with cystectomy or radiation therapy. Following radiation therapy patients will often have severe side effects from the treatment. Studies have suggested that simultanously treatment with androgen deprivation therapy during radiation therapy may be able to proctect stemcells in the bladder, thus improving tissue recovering post-radiation, …

18 years and older Male Phase N/A
J Jennifer D Dean, MS

Accuracy of Cardiac Acoustic Biomarkers Recorded by the Wearable Cardioverter Defibrillator

Evaluate data accuracy of cardiac acoustic biomarkers (CABs) recorded by the Wearable Cardioverter Defibrillator (WCD) as compared to the AUDICOR AM acoustic cardiography recorder.

18 years and older All Phase N/A
N Naima Imam, PhD

Leukocyte MOrphology and CORticosteroids Response in SEPtic Patients (MOCORSEP)

Non-interventional, prospective, monocentric study on the exploration of leukocyte morphological parameters according to the infectious condition and response to corticosteroid therapy of septic patients.

18 years and older All Phase N/A
A Anne-Hélène saliou

Medical Termination of Pregnancy : Evaluation of Patients' Practices and Feelings in Brest Hospital

This study evaluate the feelings of patients about a medical termination of pregnancy that they experienced in Brest Hospital. Patients responded to an online questionnaire assessing their feelings at each stage of the medical termination process. Their answers were associated with their medical data.

100 years and younger Female Phase N/A

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