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Found 3,739 clinical trials

S Sabine Hazan, MD

A Pilot Study to Explore the Role of Gut Flora in Gout

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.

100 years and younger All Phase N/A
H Hongzhou Lu, Ph.D

NAFLD in HIV-infected Patients

The prevalence of NAFLD (nonalcoholic fatty liver disease) in HIV-infected patients is higher than that in general population, but the causes of morbidity and pathogenesis have not been fully explored. The investigators are planning to consecutively enroll 400 cases HIV-positive outpatients, and to detect NAFLD by ultrasound. The fecal and …

18-70 years All Phase N/A
L Loreto Gesualdo, MD

Innovative Approach to Fecal Microbiota Transplantation (FMT) Applied for Chronic Kidney Disease (CKD)

The aim of this PhD project focuses on the relationship between intestinal microbiota and health in the background of Chronic Kidney Disease (CKD). Many pathologies, including the CKD, display a dysbiosis of the intestinal microbiota, which is at the same time a consequence of CKD and contributes to its progression …

18-50 years All Phase N/A
S Sabine Hazan, MD

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBS

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.

100 years and younger All Phase N/A
P Petr Hříbek, MD

Novel Molecular Spectrometric Biomarkers in Blood Plasma as an Early Diagnostic Tool in HCC

Due to providing valuable clinical information while being minimally invasive, blood-based testing will most likely be a prerequisite for future large-scale screening of high-risk populations. As a variety of pathological processes, including carcinogenesis, may cause changes in both the concentration and the structure and spatial arrangement of body biomolecules, the …

18-80 years All Phase N/A
S Stephen Kelleher, MD

The Effect of Pediatric Patient Temperament on Postoperative Outcomes

The goal of this study is to determine if preoperative temperament is associated with postoperative pain, emergence agitation, emotional and behavioral changes, and overall parent satisfaction. This is a prospective observational study to assess preoperative temperament in pediatric patients undergoing tonsillectomy and adenoidectomy, gather demographic data, intraoperative data regarding surgical …

2-7 years All Phase N/A
C C Ola Landgren, MD, PhD

Stopping Maintenance Therapy in People With Multiple Myeloma in MRD-Negative Remission

This study will test whether stopping maintenance therapy in people with multiple myeloma in MRD-negative remission has the same effect on disease control as continuing this therapy. The study will look at whether people currently on maintenance therapy can safely stop this treatment and continue with active surveillance instead while …

18 years and older All Phase N/A
K Ke-Cheng Chen, M.D., Ph.D.

Evaluation of the Cell Detachment Ratio on pH-responsive Chitosan as a Prognostic Factor in Lung Cancer

Biomaterial-based cell culture models have been gaining increasing attention as potential therapeutic strategies. The purpose of this project is to evaluate whether the cell detachment ratio on pH-responsive chitosan could be correlated with the overall survival in lung cancer patients. Through controllable cell-material interaction, this project has the intention to …

20-70 years All Phase N/A
J John Oslund

Dr. Amplatz Micro Plug - Post Market Clinical Follow-up (PMCF) Plan

This is an observational, post market clinical follow-up (PMCF) intended to evaluate the residual risks of the Dr. Amplatz Micro Plug which is intended for use during arterial embolization of the peripheral vasculature. This PMCF will collect data pertaining to any adverse events as well as the identification of any …

18 years and older All Phase N/A
P Philippe Gorphe, MD

IMRT and Primary Transoral Surgery in the Treatment of Squamous Cell Carcinomas

Compare patients' feelings in terms of swallowing ability assessed by the overall score of MD Anderson Dysphagia Inventory (MDADI) 2 years after starting treatment between patients who have been treated with IMRT and those who were treated by transoral surgery for a squamous cell carcinoma of the early stage oropharynx.

18 years and older All Phase N/A

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