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Found 3,739 clinical trials

L Louise Allen

Co-designing and Evaluating a Real-world Implementation Model for Remote Consultation with Vision Self-testing.

This study aims to involve the public, patients and National Health Service (NHS) staff in co-designing a scalable, inclusive and sustainable implementation model for ophthalmic remote consultation with vision self-testing (the intervention). The main study questions are:What are the barriers to uptake of the intervention and how can these be …

4 years and older All Phase N/A
A Abdellah AT TEBANI, Professor

Dynamics of the Urinary Bacterial Microbiota

Urinary tract infections (UTIs) are one of the most common bacterial infections in humans (Flores-Mireles et al., 2015). They rank first among healthcare-associated infections (Daniau et al., 2020) and second among community-acquired infections. Their diagnosis is based on the presence of urinary symptoms, confirmed by performing a urine culture culture …

18-45 years Female Phase N/A

FAPI Imaging Predicts Adverse Cardiac Events in Chronic Total Occlusion

Prospective, observational, single-center cohort studyHypothesis Higher myocardial FAPI uptake in CTO patients predicts a greater incidence of major adverse cardiovascular events (MACE) within 12 months after PCI. FAPI PET/CT imaging is associated with plaque vulnerability features and may serve as a non-invasive marker for fibrotic activity and adverse cardiac remodeling.Inclusion …

18 years and older All Phase N/A
H Harmony R Reynolds, MD

Heart Attack Research Program- Imaging Study

The HARP study is a multi-center, diagnostic observational study employing standardized imaging protocols in patients with MINOCA (MI with Non Obstructive Coronary Arteries) to determine the underlying diagnosis in each participant. Participants will be followed for recurrent clinical events, every 6 months, for a maximum of 10 years.

21-99 years All Phase N/A

TORNADO-Omics Techniques and Neural Networks for the Development of Predictive Risk Models

The goal of this observational study is to define a personalized risk model in the super healthy and homogeneous population of Italian Air Force high-performance pilots. This peculiar cohort conducts dynamic activities in an extreme environment, compared to a population of military people not involved in flight activity. The study …

26-38 years All Phase N/A
N Nisha A Gilotra, MD

Heart Failure Event Advance Detection Trial

Patients who are admitted with acutely decompensated heart failure and are receiving intravenous diuretics will be recruited to undergo testing using the Indicor Device. Participants will be tested daily while hospitalized and then on the day of discharge during which time they will be trained how to operate the device. …

18 years and older All Phase N/A
P Pratik Kalsaria, MS

Registry of Amniotic Membrane: Evaluating Utilization and Outcomes in Various Applications

This registry will assess clinical outcomes following the use of Cryopreserved Amniotic Membrane (CAM) for the treatment of orthopedic and various other conditions. This registry will collect outcomes data via a registry of up to 100 patients who have received treatment with CAM in the post-market setting. Patients will be …

22 years and older All Phase N/A
L Lori Barganier, BSN

Childhood Allergy and the Neonatal Environment

The purpose of this research study is to study the relationship between childhood asthma, allergies, and early-life environmental factors that may cause childhood asthma and allergies. Previous birth cohort studies have found early-life environmental factors such as allergies, pollutants, viruses and bacteria have all contributed to the development of asthma …

100 years and younger All Phase N/A
E Evelynne S Fulda, BA

Inflammation and Cardiovascular Health in Women

Systemic immune activation and inflammation are believed to play a significant role in the development and clinical course of myocardial infarction (MI). Among women with HIV (WHIV), heightened systemic immune activation and inflammation persist, even when HIV infection is well-treated with contemporary antiretroviral therapeutic regimens. Moreover, WHIV in high-resource regions …

40-79 years Female Phase N/A
S Sabine Hazan, MD

A Pilot Study to Explore the Role of Gut Flora in Eczema

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding eczema.

18 years and older All Phase N/A

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