Found 1431 clinical trials
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic amyloid deposition using the PET tracer [C-11]PiB in participants in the UAB Alzheimer's Disease Center cohort. Assessment of interactions between race and vascular risk factors, brain amyloid levels measured with [C-11]PiB-PET, and …
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- 16 Feb, 2024
- 1 location
Metformin for Abdominal Aortic Aneurysm Growth Inhibition
A multi-centre population-based open-label randomized controlled trial with allocation concealment and blinded outcome assessment will examine if up to 2g metformin daily slows AAA growth in patients with small AAAs who do not have diabetes.
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- 16 Feb, 2024
- 1 location
Histopathologic Effect of Calcium Electroporation on Cancer in the Skin
In this phase II study we investigate the effect of calcium electroporation on cancer in the skin investigated by histopathology.
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- 16 Feb, 2024
- 1 location
A Study of PLB1001 in Non-small Cell Lung Cancer With c-Met Dysregulation
This is a Phase II, open-label, multicenter and multi-cohorts study of PLB1001 administered orally twice daily to locally advanced/metastatic NSCLC patients with c-Met dysregulation.
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- 16 Feb, 2024
- 1 location
Evaluation of Staff COVID-19 Wellbeing Centres in a Healthcare Workplace: COVID-WELL Study
Evaluation of a workplace intervention to implement supported wellbeing centres in a healthcare workplace during and after the COVID-19 pandemic. Mixed-Methods Evaluation study - including collection of service use monitoring data, online survey and qualitative interviews.
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- 16 Feb, 2024
- 1 location
Iatrogenic Atrial Septal Defect Study (iASD)
This is an open-label, randomized, controlled trial of iatrogenic atrial septal defect closure with the an atrial septal occluder versus usual care observation in patients post-mitral valve intervention requiring large bore transspetal access.
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- 16 Feb, 2024
- 1 location
Oral Oxytocin's Effects on Attention Control
The main aim of the study is to investigate whether orally administered oxytocin (24IU) could modulate attention control using a social-emotional saccade/antisaccade eye-tracking paradigm.
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- 16 Feb, 2024
- 1 location
Safety and Efficacy Evaluation of ET-01 Transplantation in Subjects With Transfusion Dependent -Thalassaemia
This is an open label, single site study to evaluate the safety and Efficacy of ET-01 Transplantation in subjects with Transfusion Dependent -Thalassaemia.
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- 05 Aug, 2020
Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study (TOPAMAD)
This study has been planned to compare the efficacy and tolerability of topiramate, a commonly used second line agent, with modified Atkins diet in children with epileptic spasms refractory to hormonal treatment, in a randomized open label study.
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- 25 Jul, 2023
- 1 location
tVNS in Long COVID-19
A prior open label study has shown that transcutaneous vagus nerve stimulation [tVNS] can improve the health of some patients with postacute sequelae of SARS-CoV-2 infection (PASC), severely affected enough to also fulfill criteria for myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS). The purpose of this study is to compare …
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- 05 May, 2025
- 2 locations