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Found 3,739 clinical trials

S Steffen Pfeuffer, Dr.

Immunoadsorption Versus High-dose Intravenous Corticosteroids in Relapsing Multiple Sclerosis

Treatment of acute relapsing multiple sclerosis (MS) has remained largely unaltered within past years. However, evidence defining the exact role of apheresis treatment in the therapeutic sequence is still incomplete. INCIDENT-MS evaluates the mechanism of action of immunoadsorption compared to escalated methyl prednisolone treatment in steroid-refractory MS relapses and thereby …

18-65 years All Phase N/A
S Shannon Chan, FRCSEd

Colonoscopy is an Aerosol Generating Procedure

With a commercially available particle counter, we can differentiate the particle counts of different sizes in different areas of the endoscopy room. An increase from baseline particles of < 5um during or after the procedure would suggest that the procedure is an AGP. In this study, the particle counter from …

100 years and younger All Phase N/A
A Aleksander Araszkiewicz, Assoc. Prof.

Catheter-directed Thrombectomy in High and Intermediate-high Risk Pulmonary Embolism

Pulmonary embolism is one of the leading causes of cardiovascular death. Pulmonary embolism may be life-threatening condition with an estimated 30-day mortality rate about 10-30%. In high-risk pulmonary embolism, systemic thrombolysis is indicated, whereas recent development of interventional cardiology has made catheter-directed techniques an important alternative to thrombolytic therapy. The …

18 years and older All Phase N/A
F Fanny BOUNES

COVID-19: Study of INFLAmmasome and PLAtelets Functions

COVID-19 pandemic is a severe viral sepsis characterized by the occurrence of Acute respiratory distress syndrome (ARDS) whose pathophysiology is little described

18 years and older All Phase N/A
L Leonardo A Bustamante, Surgeon

Which Type of Laparoscopic Colectomy Right or Left Have Better Postoperative Outcomes for the Patients?

Laparoscopic surgery decreased the morbidity of colorectal surgery. The two most common surgeries for colorectal cancer are right and left colectomy. Objective: To compare perioperative morbidity of the right versus left colectomy for cancer, as well as the quality of laparoscopic oncologic resection of both procedures. Methods: Retrospective analysis of …

18-80 years All Phase N/A
J Jean DELLAMONICA

AiCR : Artificial Intelligence in Cardiac aRrest

The overall incidence of cardiorespiratory arrest in Europe is estimated at 350,000 to 700,000 cases per year. Survival rate is estimated at 10.7% for all rhythm disorders combined. Several examples of AI application in the medical field exist. Ting et al have developed a computer tool capable of diagnosing the …

18 years and older All Phase N/A
H Hongwei Li, M.D

Effect of Covid-19 Epidemic on Primary PCI in Patients With STEMI

The epidemic of covid-19 has spread all over the world and has a great impact on people's health and life. It is necessary to study the treatment of STEMI patients in the real world under the influence of the epidemic,which provide effective suggestions and strategies for emergency and severe treatment.

100 years and younger All Phase N/A
D Dong-Jun Lim

Change of Gut Microbiome in the Treatment of Graves' Disease

Graves' disease is the main cause of hyperthyroidism. Graves' disease has a prevalence of 0.5% in the general population. As a non-surgical treatment, antithyroid drug (ATD) and radioactive iodine treatment have been proposed and ATD is the first-line treatment in Korea. However, ATD has a rare but fatal side effect …

19-69 years All Phase N/A
S Sergey L Andreev, researcher

The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy

The study focuses on the development of a new personalized approach to diagnostics and surgical treatment of patients with ischemic cardiomyopathy. The algorithm for selection of patients for certain type of cardiac surgery will be developed. The models for prediction of the risks and outcomes of cardiac surgery will be …

18-70 years All Phase N/A
S Stefania Fugazzaro, MD

Rehabilitation Needs After COVID-19 Hospital Treatment

The onset of Coronavirus Disease 2019 (COVID-19) in the first months of 2020 had a huge impact on Italian population and Healthcare System, with more than 150.000 total confirmed cases1. SARS-CoV-2 is a highly contagious new virus, causing an influenza like illness and respiratory tract infection demonstrating fever (89%), cough …

18 years and older All Phase N/A

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