Found 3051 clinical trials
RCT for Electroconvulsive Treatment Followed by Cognitive Control Training
As such, cognitive control training (CCT) holds promise as a non-pharmacological strategy to improve long-term effects of ECT (i.e., increase remission, and reduce depression relapse).
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- 05 Aug, 2020
Computerised Behavioural Activation for Young People With Depression
The primary aim of this non-randomised feasibility study is to 1) examine the acceptability of a newly developed computerised Behavioural Activation programme (BALM) in treating young people experiencing low mood/depression and 2) assess the feasibility of undertaking a pilot Randomised Controlled Trial (RCT) of the intervention.
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- 16 Feb, 2024
- 1 location
Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)
Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by double-blind, randomized adjunctive treatment with clonazepam or pregabalin for persistent symptoms.
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- 16 Feb, 2024
- 1 location
Ketamine or Placebo in Patients With Major Depression and Advanced Cancer
Major depression (MD) is a psychiatric disorder characterized by a persistent feeling of sadness, anhedonia or a decreased perception of pleasurable experiences, as well as appetite alterations and weight variations, sleep disorders, altered psychomotor skills, fatigue, guilt, decreased self-worth, suicidal thoughts and difficulty concentrating in a task (1).
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- 16 Feb, 2024
- 1 location
Mind-Body Medicine for the Improvement of Quality of Life in Adolescents and Young Adults Coping With Hodgkin Lymphoma
A meditation based mind-body intervention may help lower distress, depressive symptoms, and anxiety in adolescents and young adults coping with Hodgkin lymphoma.
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- 16 Feb, 2024
- 1 location
Open-label Flexible-dose Study of Vortioxetine in Patients With Depression in India
The purpose of this study is to evaluate the safety and tolerability of flexible doses of vortioxetine (5 - 20 mg/day) over a period of 12 weeks in patients with depression in India
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- 16 Feb, 2024
- 8 locations
Psychotherapy (Accelerated Resolution Therapy) for Cancer Related Trauma and Distress
Accelerated resolution therapy is an evidence-based therapy for the treatment of depressive symptoms, trauma, and stress-related disorders. This study may provide evidence to support integration of accelerated resolution therapy into psychological treatment of cancer patients, which may decrease cancer related trauma and distress.
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- 16 Feb, 2024
- 1 location
iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of Treatment
This is an open label, pilot, feasibility study evaluating effects of Intermittent Theta Burst Transcranial Magnetic Stimulation (iTBS) on 5 eligible adolescents for the treatment of depression. Safety and tolerability will be evaluated with changes in depression scores, and suicidality and non-suicidal self injurious behavior will also be monitored for …
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- 05 Aug, 2020
Feasibility and Effectiveness of Delivering Cognitive Behaviour Therapy Through Online Psychotherapy Tool (OPTT) for Depression
To the principal investigators' knowledge, this study will be the first multi-site study examining the efficacy of e-CBT in depression compared to pharmacotherapy using a naturalistic research design.
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- 16 Feb, 2024
- 1 location
Mechanism of Action of Transcranial Magnetic Stimulation
This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.
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- 16 Feb, 2024
- 1 location