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Found 3,739 clinical trials

K Kassiani Theodoraki, PhD, DESA

Prevention of Maternal Hypotension During Cesarean Section With Norepinephrine Infusion.

This will be a randomized study aiming at investigating the combination of a norepinephrine infusion and colloid preloading versus the combination of a norepinephrine infusion and crystalloid co-loading for the prevention of maternal hypotension during elective cesarean section

18-48 years Female Phase N/A
L Li Wang, M.D., Ph.D

Lenalidomide in Combination With CHOP in Patients With Untreated PTCL

The prognosis of PTCL (except early stage ALK+ ALCL) is dismal. Previous study showed that single agent lenalidomide showed promising therapeutic activity in patients with relapsed or refractory PTCL. The investigators therefore design this phase II study to investigate the safety and efficacy of lenalidomide in combination with CHOP in …

18-70 years All Phase 1/2
P Pedro Gomez

Internal Limiting Membrane Peeling in Proliferative Diabetic Retinopathy

Subject/Participant Groups: Study Group: Subjects undergo internal limiting membrane (ILM) peeling during vitrectomy for the indication of tractional retinal detachment Control Group: Subjects do not undergo ILM peeling during vitrectomy for the indication of tractional retinal detachment

18-85 years All Phase N/A
R Research Coordinator

Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease

Impaired verbal communication is a cardinal symptom of Alzheimer Disease (AD) and the source of enormous distress and disability. Effective therapies for this deficit are lacking. In light of the emerging literature demonstrating that Transcranial Magnetic Stimulation (TMS) improves general cognition in subjects with Alzheimer Disease (AD), the investigators propose …

60-85 years All Phase 1
A Amal Naous, MD

Analgesic Effect of Oral Glucose in Neonates

Background: Male circumcision is one of the oldest and most common operations performed all over the world. It can be performed at different ages, using different surgical techniques, for different religious, cultural and medical reasons. It was thought that the newborn baby does not experience pain because of incompletely developed …

1 years and younger Male Phase N/A
J Jamie Cooper, PhD

Oil Consumption and Cholesterol

More than 31 million U.S. adults have high total cholesterol and over 73 million U.S. adults have high LDL cholesterol. Cottonseed oil (CSO) is found readily in our food supply, and recent research has shown improvements in blood lipids following CSO consumption in healthy adults with normal cholesterol profiles. To …

30-75 years All Phase N/A
E Eline Meireson, Msc

Study to Evaluate the Learning Curve to Anchor GYN-CS Device

GYN-CS is a new concept in intrauterine device technology. It is fixed to the uterine fundus, is frameless and entirely flexible. The GYN-CS 3 has a lifespan of 3 years and GYN-CS 10 has lifespan of 10 years, both used in this study. The primary objectives are: Analyse the learning …

18-48 years Female Phase N/A
C Chelsea Harrison, DPT

Long Term Functional Outcomes of COVID-19 Patients Treated by Rehabilitation Services viaTelehealth

This study seeks to assess the impact of physical and pulmonary rehabilitation on patients who have been diagnosed with COVID-19 in the short and long term in hopes of establishing a best practices protocol for treatment of future patients with this disease.

18 years and older All Phase N/A
R Rupa Chowdary

GLS-1200Topical Nasal Spray to Prevent SARS-CoV-2 Infection (COVID-19) in Health Care Personnel

This clinical trial will evaluate the safety, tolerability and effectiveness of topical GLS-1200 nasal spray to reduce the incidence of confirmed, symptomatic SARS-CoV-2 infection.

18 years and older All Phase 2
N Navin Pinto, MD

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

26 years and younger All Phase 1

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