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Found 2080 clinical trials
TKR Rehabilitation Through the Immersive Virtual Reality in Aquatic Scenarios

This study is a multicenter non-randomized single-blind controlled trial, aimed at investigating the feasibility and efficacy of hydrotherapy based on IVR, for the patients with TKR, on the function, gait performance, postural balance control, and knee edema reduction. The protocol was draft according to the Consolidated Standards of Reporting Trials …

hydrotherapy
cognitive disorders
edema
drainage
edema reduction
  • 0 views
  • 16 Feb, 2024
  • 1 location
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts the body and is PD-L1-negative. The names of the study interventions involved in this study are: Sacituzumab govitecan (IMMU-132) Pembrolizumab (Keytruda; MK-3475)

central nervous system disease
breast cancer
sacituzumab govitecan
brain metastases
HER2
  • 8 views
  • 05 Aug, 2020
Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms

The study is a prospective, randomized, controlled investigation designed for comparison of two groups for the reduction of respiratory distress in a CoViD-19 population, using gammaCore Sapphire (nVNS) plus standard of care (active) vs. standard of care alone (SoC), the control group. The gammaCore (nVNS) treatments will be used acutely …

dyspnea
cough
covid-19
oximetry
respiratory distress
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study With Pembrolizumab for Non-small Cell Lung Cancer (NSCLC)

This study is a randomized, national multicenter clinical study which is designed to compare the efficacy of the safety and efficacy of treatment every 3 weeks or 6 weeks in (Non-small-cell-cell cancer, NSCLC) subjects without systematic treatment who used Pembrolizumab after 6 cycles of combined chemotherapy estimated with stable efficacy …

  • 0 views
  • 05 Aug, 2020
Efficacy and Safety Study of Dupilumab in Patients With Persistent Asthma

Primary Objective: To evaluate the efficacy of dupilumab in patients with persistent asthma Secondary Objectives: To evaluate the safety and tolerability of dupilumab To evaluate the effect of dupilumab on improving patient reported outcomes including health related quality of life To evaluate dupilumab systemic exposure and immunogenicity

bronchodilator
fractional exhaled nitric oxide
persistent asthma
corticosteroids
dupilumab
  • 0 views
  • 04 Dec, 2020
  • 64 locations
Effect of Nutritional Supplementation and Pulmonary Rehabilitation on the Clinical Status of HF and COPD

Cardiovascular diseases (CVD) are the leading cause of death in the world and our country. The prevalence of Heart Failure (HF) is 1-2% in the adult population in developed countries, up to 10% among people 70 years of age. Concerning COPD, it is estimated that by 2030 will be the …

heart failure
pulmonary disease
pulmonary function test
post bronchodilator spirometry
leucine
  • 0 views
  • 16 Feb, 2024
  • 1 location
Renal Denervation in Chronic Kidney Disease - RDN-CKD Study

RDN-CKD Study is a prospective, randomized (1:1, central randomization), double-blind (unblinded interventionalist and blinded study team at each center), sham controlled, multicenter feasibility study. The purpose of the RDN-CKD Study is to demonstrate that renal denervation (RDN) effectively reduces 24-h ambulatory BP in 80 patients with chronic kidney disease (CKD) …

  • 0 views
  • 16 Feb, 2024
  • 4 locations
Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma

The objective of this study is to evaluate, in patients diagnosed with prostate cancer who undergo radical prostatectomy and who require postoperative radiotherapy, tolerance in terms of acute and chronic GU and GI toxicity and efficacy in terms of biochemical control and survival, as well as of quality of life, …

immunological adjuvant
bone scan
prostatectomy
adjuvant
carcinoma
  • 0 views
  • 16 Feb, 2024
  • 19 locations
De-escalated Conformal Radiation Expedited Sequentially With Chemotherapy for Endometrial Cancer

The goal of this study is to evaluate short course radiation in the post-operative female pelvis after hysterectomy in stage III-IVA endometrial adenocarcinoma patients, or any stage patients with uterine serous or carcinosarcoma histology. The investigators hypothesize that short course pelvic radiation will have an acute and late grade 3-4 …

pelvic radiation
absolute neutrophil count
endometrial cancer
adenocarcinoma
endometrial adenocarcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma

This trial is a multi-center, phase III, randomized (1:1) clinical trial. The aim is to explore the efficacy and safety of SBRT for perivascular hepatocellular carcinoma, compared with RFA.

radiofrequency ablation
stereotactic body radiation therapy
recurrent hepatocellular carcinoma
carcinoma
hepatocellular carcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location