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Found 1804 clinical trials
Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID 19 Prediction of Outcome

To ascertain globally the changes in the cytokines involved and TLRs/KIR activation in patients admitted to the hospital with a COVID-19 diagnosis, and the changes after initiation of the different therapies

cytokines
covid-19
  • 0 views
  • 16 Feb, 2024
  • 1 location
Predicting Response to Interventional Pain Management Techniques in Chronic Low Back Pain in a Prospective Cohort.

The main aim of this study is to identify factors that may be associated with a better or worse response to interventional pain management therapies for the treatment of chronic lumbar pain in adult patients. If several predictive factors are to be identified, a predictive model will be developed.

corticosteroids
back pain
radiofrequency denervation
facet joint injection
intra-articular injection
  • 0 views
  • 05 Aug, 2020
Cancer Therapy Effects on the Heart

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies for identifying patients who are at risk prior to …

pediatric
daunorubicin
cardiotoxicity
childhood cancer
anthracycline
  • 0 views
  • 16 Feb, 2024
  • 1 location
B3 for NMD: Bench to Bedside and Back

Objective: The purpose of this study is to identify genetic or other markers in patient biosamples (e.g. blood, muscle, skin samples), electrodiagnostic studies or imaging that may help physicians and scientists provide faster ways to diagnose patients with NMD, study disease progression, and discover underlying disease mechanisms that may lead …

amyotrophic lateral sclerosis
spinal muscular atrophy
neuromuscular diseases
motor neuron disease
neuropathy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Longitudinal COVID-19 Cohort Study

Understanding these features of COVID-19 will improve the ability to design acute therapies and recovery-focused interventions. To address these knowledge gaps, the investigators propose a two-center, 225 patient longitudinal prospective cohort study of hospitalized COVID-19 patients with acute respiratory failure.

acute respiratory syndrome (sars)
SARS
acute respiratory failure
respiratory distress
acute respiratory distress
  • 0 views
  • 05 Aug, 2020
Highly Suppressive Treg in Delayed and Slow Graft Function After Kidney Transplantation

Ultimately, marginal kidney graft allocation could be directed to regulatory T cell-robust recipients and regulatory T cell-directed therapies could decrease marginal kidney graft discards without increasing delayed/slow graft function or impacting outcomes.

kidney transplant
ischemia
ischemic reperfusion injury
graft failure
ischemia-reperfusion injury
  • 0 views
  • 05 Aug, 2020
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)

They want to understand how adrenocortical cancer appear on imaging scans, how they respond to therapies, and the best treatment for them. Objective To gain a better understanding of adrenal cancer.

adrenal
cancer
blood tests
adrenocortical carcinoma
solid tumors
  • 0 views
  • 16 Feb, 2024
  • 1 location
Cardiac Arrest Incidence and Outcome Among Patients With COVID-19 in French ICUs

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the novel coronavirus disease 2019 (COVID-19) pandemic. Among COVID-19 complications, in-hospital cardiac arrest (IHCA) was reported with a very poor outcome in a retrospective single-center study (0,7% of 30 days survival with good neurological outcome among IHCA patients with a …

acute respiratory syndrome (sars)
SARS
resuscitation
coronavirus infection
covid-19
  • 0 views
  • 16 Feb, 2024
  • 41 locations
Evaluation of Eosinophil Phenotype in COPD Patients

This is a pilot non pharmacological observational study. Aim of the study is to analyze the immunophenotype of circulating eosinophils in chronic obstructive pulmonary disease (COPD) patients, and to correlate results with clinical status of patients (stable versus exacerbated patients, response to therapy). In about 30% of COPD patients there …

cytokines
pulmonary disease
flow cytometry
lung disorder
eosinophil count
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluating the Role of Inflammation in Neonatal Epileptogenesis

The purpose of this study evaluate the relationship between inflammation and epilepsy in neonates with seizures after birth.

acute brain injury
encephalopathy
seizure
inflammatory response
eeg monitoring
  • 0 views
  • 16 Feb, 2024
  • 4 locations