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Found 1831 clinical trials
Diagnostic Value of D-dimer/Fibrinogen Ratio in Patients With Acute Aortic Dissection

Therefore prompt diagnosis is crucial. D-dimer values have been shown to be useful in the diagnosis of acute aortic dissection. Fibrinogen levels have been shown to be low, normal or high in individuals with acute aortic dissection.

acute pulmonary embolism
embolism
acute aortic dissection
acute aortic dissections
d-dimer
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Serial Tumour Biopsies and Blood Biomarkers in Melanoma

The study will be open to NHS patients aged 16 and over, who have been diagnosed with advanced melanoma, and who will be receiving treatment for their disease as part of their routine care.

advanced melanoma
blood test
cancer treatment
cancer
metastatic malignant melanoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Kinematic Versus Mechanical Alignment in Total Knee Replacement

This prospective controlled double-blind randomized study compares kinematic and mechanical alignment in TKA (Total knee arthroplasty). A total of 120 patients will be included and the surgery will be performed using CT based 3D printed PSI(Patient Specific Instruments) Cutting guides.

osteoarthritis
total knee replacement
  • 0 views
  • 05 Aug, 2020
Epidemiological Study of the Microbiota in Critically Ill Children (n=100) From 1 to 16 Years Compared With Healthy Controls (n=50) and Its Relationship With Clinical Complications and Inflammatory Biomarkers

Clinical parameters and rectal, fecal, blood and respiratory samples will be collected at admission and at pediatric intensive care units discharge. The microbiota and inflammation biomarkers and metabolomic will be analyzed.

  • 0 views
  • 05 Aug, 2020
Anxiety and Depression Disorder in Patient Treated With rTPA for Mangment of Acute Ischemic Stroke

In fact theWorld Health Organization estimates that 2-3% in general populations of countries across the world tend to be affected by severe mental disorders (1) Thrombolytic therapy seems to be of great importance in achieving better quality of life in ischemic stroke patients who respond to this therapy(rTPA).

psychiatric disorder
depression
mental disorders
actilyse
thrombolytic
  • 0 views
  • 16 Feb, 2024
  • 1 location
Glycaemia and Cardiac Function in Patients With COVID-19

In the medical ward cohort, two assessments will be performed separated by no more than 12 hours. In the ICU cohort, three assessments will be performed separated by no more than 6 hours.

type 2 diabetes mellitus
covid-19
plasma glucose measurement
plasma glucose
atrial fibrillation
  • 0 views
  • 05 Aug, 2020
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1a

This study seeks to address this public health issue. Breastmilk will be collected from mothers positive for COVID-19. Samples will be analyzed for the COVID-19 virus specific nucleic acid and antibody in real-time and results will be immediately disseminated to relevant organizations to inform local, national and international guidelines surrounding …

covid-19
  • 0 views
  • 01 Feb, 2023
  • 2 locations
Impact of Sinus Surgery on Individuals With Cystic Fibrosis

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS).

cystic fibrosis
sinusitis
sweat chloride
rhinosinusitis
sweat chloride test
  • 0 views
  • 16 Feb, 2024
  • 1 location
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

A small piece of skin may be removed.A skin or blood sample may be taken to create stem cells.Optional lumbar puncture. A needle will be inserted into the space between the bones of the back to collect fluid.

  • 0 views
  • 19 Feb, 2025
Towards Targeting the ORigin of the Inflammatory Cascade in Allergic Asthma

In addition, blood and nasal epithelial brushes will be obtained to study the genetic and epigenetic mechanisms of asthma. Finally, bronchoscopy with bronchial biopsies and brushes will be performed under conscious sedation.

albuterol
bronchoscopy
respiratory symptom
dyspnea
bronchodilator
  • 0 views
  • 16 Feb, 2024
  • 1 location