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Found 216 clinical trials
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Major depressive disorder (MDD) is a common, recurrent, and frequent chronic disorder. Treatment is often challenging; up to 40% of patients do not benefit sufficiently from existing antidepressant interventions including trials of medication and psychotherapy. Up to 25% of patients manifest a chronic course of illness, resulting in a need …

  • 0 views
  • 09 Jul, 2021
Study of Tumor Infiltrating Lymphocytes Following CCRT in the Treatment of Patients With Cervical Carcinoma

A Phase II trial to study the effectiveness and security of cisplatin concurrent chemoradiotherapy plus TIL versus cisplatin concurrent chemoradiotherapy only in treating patients with FIGO stage IIIA to IVA cervical carcinoma.

chemoradiotherapy
concomitant radiochemotherapy
cervical carcinoma
cancer
squamous cell carcinoma
  • 0 views
  • 05 Aug, 2020
Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma

This is a phase III randomized clinical trial of definitive radiotherapy plus EGFR blocker nimotuzumab versus radiotherapy plus cisplatin(CCRT) for nasopharyngeal carcinoma (NPC) patients with favorable response to induction chemotheray(IC), determining whether radiotherapy combined with nimotuzumab was non-inferior to CCRT and may provide new evidence for individualized comprehensive treatment of …

epstein-barr virus dna
EGFR
induction chemotherapy
nasopharyngeal carcinoma
renal function test
  • 0 views
  • 16 Feb, 2024
  • 1 location
Axon - Brain Train for Pain

A mixed methods proof of concept study to ascertain the effectiveness of a home-based self-administered neurofeedback intervention to treat the primary and secondary symptoms of chronic pain.

neurofeedback
brachial plexus injury
epilepsy
mental illness
systemic infection
  • 0 views
  • 05 Aug, 2020
Assessing the Rate of Complications in X-Ray Therapy Versus Proton Beam Radiation Therapy After Breast Conserving Surgery or Mastectomy in Treating Patients With Breast Cancer

This phase II trial investigates the rate of complications of x-ray therapy versus proton beam radiation therapy after breast conserving surgery or mastectomy in treating patients with breast cancer. X-ray therapy is a form of radiation therapy that uses high-energy radiation from x-rays to kill tumor cells and shrink tumors. …

stage iiib breast cancer
stage iib breast cancer
prognostic stage ia breast cancer ajcc v8
anatomic stage ib breast cancer ajcc v8
anatomic stage ii breast cancer ajcc v8
  • 0 views
  • 05 Jan, 2021
Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma

This is the first phase II randomized clinical trial of concurrent chemoradiotherapy with or without EGFR blocker Nimotuzumab for high risk advanced nasopharyngeal carcinoma(NPC) , determining whether concurrent chemoradiotherapy(CCRT) combined with nimotuzumab can improve the survival rate of high-risk patients and may provide new evidence for individualized comprehensive treatment of …

epstein-barr virus dna
chemoradiotherapy
EGFR
induction chemotherapy
nasopharyngeal carcinoma
  • 4 views
  • 16 Feb, 2024
  • 1 location
P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

An open-label, multi-center, single and cyclic ascending dose study of P-PSMA-101 autologous CAR-T cells in patients with mCRPC.

metastatic disease
measurable disease
metastasis
rimiducid
metastatic cancer
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Prehabilitation for Gastrectomy

Prehabilitation has been demonstrated to be an effective strategy to improve outcomes in patients undergoing some of the abdominal operations. It may increase the physical capacity of the patient, improve postoperative quality of life and even decrease the postoperative morbidity. Currently, the most effective strategy seems to be a trimodal …

gastric cancer
cancer
gastrectomy
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Radiotherapy With Hyperthermia in Recurrent and Radiation-Induced Sarcomas

After a screening, which consists of biopsy, physical examination, initial diffusion-weighted magnetic resonance imaging (DWI-MRI) or body computed tomography (CT) scan, blood tests and case analysis on Multidisciplinary Team (MDT) meeting, a patient with radiation-induced or in-field recurrent sarcoma will receive the hypofractionated radiotherapy with deep hyperthermia (twice a week) …

ct scan
MRI
soft tissue sarcoma
recurrent soft tissue sarcoma
recurrent sarcoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Durvalumab(MEDI4736) After chemoRadioTherapy(DART) for NSCLC-a Translational and Biomarker Study

The main aim is to identify and describe biomarkers in different sample types related to chemoradiation followed by durvalumab treatment for stage III PD-L1 negative and positive non-small cell lung cancer (NSCLC) patients' eligible for curatively intended chemoradiation. The hypothesis is that clinical differences in course of disease reflect underlying …

chemoradiotherapy
urine test
stage iii non-small cell lung cancer
serum pregnancy test
neutrophil count
  • 0 views
  • 16 Feb, 2024
  • 2 locations