Found 3,739 clinical trials

D Daiichi Sankyo Contact for Clinical Trial Information

A Study of DS-1001b in Patients With Chemotherapy- and Radiotherapy-Naive IDH1 Mutated WHO Grade II Glioma

This Phase 2 study is conducted to assess the efficacy and safety of DS-1001b in patients with chemotherapy- and radiotherapy-naive IDH1 mutated WHO grade II glioma.

20 years and older All Phase 2

J J Hee Hong

Optic Nerve Sheath Diameter Difference Between Different Injection Volume

Valid method of indirect measurement of intracranial pressure is using optic nerve sheath diameter. Different volume of injection is known to affect the degree of increase of intracranial pressure. This study is desinged to measure the changes of optic nerve sheath diameter and cerebral oxygenation when different volume of normal …

20-80 years All Phase N/A

A Andre Brodkorb, PhD

Digestion of Gluten in the Presence of Enzymes

This study evaluates the impact of two dietary supplements (Glutalytic and DE111) and of oatmeal properties on the digestion of gluten and starch and on the glycemic response.

18-75 years All Phase N/A

C Christian Grommes, MD

Nivolumab Maintenance in Newly Diagnosed PCNSL With Persistent CSF Circulating Tumor DNA After Completion of First-Line Chemotherapy

The purpose of this additional part of the study is to test whether the study drug, nivolumab, is a safe treatment that will prevent participants' primary central nervous system lymphoma (PCNSL) from growing again (recurrence). Participants will be people with PCNSL who continue to have cell free tumor DNA (cfDNA) …

18 years and older All Phase 2

K Kenneth E. Thummel, PhD

Vitamin K Supplementation Study in Healthy Volunteers (Aim 2B)

The overall purpose of this study is to determine how variation in the CYP4F2 gene modulates the synthesis of vitamin K-dependent clotting factors. We propose that the CYP4F23 gene variant increases short- and long-term vitamin K concentrations in the liver by reducing the efficiency of vitamin K metabolism. The investigators …

18 years and older All Phase N/A

J Jessica Scott, PhD

Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer

This study will compare the effects on cardiorespiratory fitness (CRF) of aerobic exercise in different amounts (number of minutes/session) over different periods of time (number of weeks). Aerobic exercise is physical activity of light-to-moderate intensity that uses the large muscle groups (muscles in your legs, buttocks, back, and chest) and …

21-80 years Female Phase N/A

C Christiane Morecock

Assessing the Sensitivity of "SureTouch " in Identifying Clinically Significant Masses in Women Undergoing Diagnostic and Screening Mammography

Prospective, case-control study being conducted to determine the sensitivity of the SureTouch device in detecting known masses at a pre-determined level of specificity.

30-80 years Female Phase N/A

l lei zhang, doctor

Effect of Preoperative Intervention With Folic Acid and Vitamin B12 on Postoperative Neurobehavioral Changes in Children

Comparison of preoperative folic acid and VitB12 intervention on postoperative delirium and long-term neurobehavioral changes in children under general anesthesia

1-1 years All Phase N/A

N Nuria Argudo, MD

Radiofrequency Ablation (RFA) in Breast Tumors

To validate the efficacy and safety of the cool-tip ablation method for breast tumors smaller than 2 cm.

65 years and older Female Phase N/A

S Sherief Abd-Elsalam, Ass. Prof.

Study of Nitazoxanide (NTZ) for Helicobacter Pylori in Children

Study of Nitazoxanide (NTZ) based therapeutic regimens for Helicobacter pylori in children

18 years and younger All Phase 3