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Found 3,739 clinical trials

M Marielle Engelen

Fiber Metabolism in Chronic Obstructive Pulmonary Disease

The impact of fiber intake on short chain fatty acid (SCFA) metabolism has not been studied in subjects suffering from COPD. The purpose of this study is to compare changes in SCFA metabolism after inulin vs. placebo intake in COPD patients to healthy matched controls. This protocol is an extension …

45 years and older All Phase N/A
B Bo-Hyung Kim

Safety and Pharmacokinetics of DWJ1439 DWJ1464 DWC202003 or DWC202004 in Healthy Volunteers

The purpose of this study is to explore the differences in pharmacokinetics and safety characteristics between Test Drugs(DWJ1439, DWJ1464) and that of Reference Drugs(DWC202003, DWC202004) in healthy adults.

19 years and older All Phase 1
M Manal Hubeish, MD

Effect of Single Dose Antenatal Betamethasone on Neonatal Respiratory Morbidity After Elective Cesarean

Patients undergoing elective C-section will be randomized into two groups. The first group will receive one dose of Betamethasone at least 24 hours before scheduled C-section. The second group will receive placebo.

17-45 years Female Phase N/A
K Kerstin Bode, M.D.

Fasting Versus Non-Fasting for Cardiac Implantable Electronic Devices (FastCIED Study)

There was no evidence to suggest that a shortened fluid fast results in an increased risk of aspiration, regurgitation or related morbidity compared with the standard 'nil by mouth from midnight' fasting policy. However, there is no available data regarding the safety and efficacy of fasting approach in patients undergoing …

18 years and older All Phase N/A
Z Zan Shen, Doctor

A Study to Evaluate the Tolerance Efficacy and Pharmacokinetics of TQB3558 Tablets

This is a study to evaluate the maximum tolerated dose (MTD) , occurrence of all adverse events (AE) and serious adverse events (SAE) , pharmacokinetic parameters and antitumor effect of TQB3558 tablets in Chinese adult patients with advanced solid tumors .The study is divided into phase Ia and phase Ib. …

18-75 years All Phase 1
A Arnaud GALBOIS, MD

Virtual Reality Hypnosis for Thoracic Drain Insertion

The main objective of this study is to evaluate, in vigilant resuscitation patients, the effect of the use of HYPNO VR on the pain felt during the insertion of a thoracic drain.

18 years and older All Phase N/A
J Jürgen Debus, Prof.

Tissue Retractors for Radiation Therapy of Head and Neck Tumors

The rate of therapy-associated side effects during and after radiotherapy of head and neck tumors is essential. The most effective approach to reducing acute toxicity is to cut out healthy tissue from the radiation field. The distance between the tumor and normal tissue can be individually increased using personalized, 3D …

18-99 years All Phase 2
B BeiGene

Comparing the Efficacy and Safety of a New Additional Treatment With Tislelizumab in Non-Small Cell Lung Cancer (NSCLC)

The primary objective of this study is to evaluate and compare major pathological response(MPR) rate and event-free survival (EFS) in participants receiving tislelizumab plus platinum-based doublet chemotherapy as the new additional treatment followed by tislelizumab as adjuvant treatment versus participants receiving placebo plus platinum-based doublet chemotherapy as neoadjuvant treatment followed …

18 years and older All Phase 3
M Manish Jain, MD

Nexplanon Removal: Subcutaneous vs. Topical Lidocaine

A randomized trial of using EMLA cream for anesthesia to remove Nexplanon versus the standard route of subcutaneous lidocaine for anesthesia. Primary endpoints are pain during procedure and time to removal.

18 years and older Female Phase 4
A Ayotola Onipede, B.S.

Peer-Led Dissonance Eating Disorder Prevention: Virtual Delivery

This proposed pilot study will evaluate whether this body acceptance class produces greater reductions in eating disorder risk factor symptoms (pursuit of the thin ideal, body dissatisfaction, dieting, dietary restraint and negative affect), eating disorder symptoms, and future onset of eating disorders over 6-month follow-up in this population.

16-26 years Female Phase N/A

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