Found 1431 clinical trials
Optimal EGFR TKIs Treatment Strategies for Lung Adenocarcinoma Harboring EGFR Exon 19 Deletion Variants
To determine the optimal EGFR TKIs treatment strategies for lung adenocarcinoma harboring EGFR exon 19 deletion variants
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- 05 Aug, 2020
The ATtune Knee Outcome Study
To accomodate dissatisfied patients with a total knee arthroplasty (TKA) and improve outcomes, several knee systems have been developed. The cemented ATTUNE TKA shows superiority over other established knee systems at short-term, abating with longer follow-up. There have been no studies reporting on the results of the uncemented version of …
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- 16 Feb, 2024
- 1 location
Multicenter Normal Reference Study of Tissue Motion Tracking of Mitral Annular Displacement(TMAD)
To establish the range of TMADmidTMADmidpt% by using tissue motion tracking of mitral annular displacement (TMAD), and to explore the influencing factors.
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- 16 Feb, 2024
- 75 locations
Early PONV - a Registry Based Study in Sweden.
The study is an registry study based on data from the Swedish Perioperative Registry (SPOR) during the years 2016-2022 with the aim to explore the risk for postoperative nausea and vomiting at the recovery unit (early PONV). The study will explore several cohorts (for example a specific procedure) on a …
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- 16 Feb, 2024
- 1 location
Longitudinal Study of Seroprevalence of SARS-CoV-2 Antibodies and Development of Immunity in School Children
There is a lack of knowledge about how many children are infected with SARS-CoV-2, how often they are asymptomatic, and how long the immunity persists. The main purpose of this study is to measure antibodies to SARS-CoV-2, symptoms, and risk factors in a representative cohort of children and adolescents in …
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- 01 Feb, 2023
- 1 location
Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19
The study will analyze the incidence, clinical outcomes and predictors of myocardial injury in a large patient population with COVID-19 treated in Mount Sinai Hospital (MSH) system. In addition, the study team will explore the association between high-sensitivity troponin I (TnI) levels and clinical characteristics, biomarkers, cardiac tests data and …
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- 16 Feb, 2024
- 1 location
COVID-19 Pandemic Impact on Alcohol (PIA) - A Natural History Study
Background The SARS-CoV-2 virus has caused a pandemic infection called COVID-19. It is a global threat to people, communities, and health systems. Researchers are concerned about the mental health effects of the pandemic. They want to learn more about how it is affecting people s alcohol use and problems, and …
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- 05 Aug, 2020
COronary and MICrocirculatory Measurements in Patients With Aortic Valve Stenosis.
Aortic stenosis (AS) is the most common primary valve disease leading to surgery or catheter intervention in Europe, with a growing prevalence due to the aging population.
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- 16 Feb, 2024
- 1 location
TMAO in Patients With Severe Aortic Stenosis
The secondary aim of this study is to evaluate a correlation between the baseline TMAO concentrations and the post-treatment clinical status, as well as the post-treatment echocardiographic and biochemical parameters.
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- 16 Feb, 2024
- 1 location
Cardiac Output, Cerebral Perfusion and Cognition in Patients With Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation (CAPITA)
Cognitive impairment is common (21-39%) among patients with severe aortic valve stenosis. The proof-of-concept CP-TAVI study showed that increased cardiac output following transcatheter aortic valve implantation (TAVI) was associated with increased cerebral blood flow.
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- 11 Jan, 2023
- 1 location