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Found 11242 clinical trials
Altered Tumor Oxygenation by Metformin a Potential Step in Overcoming Radiotherapy Resistance in LACC

Poor tumor oxygenation (hypoxia) is an established negative prognostic and predictive factor in locally advanced cervical cancer (LACC). Hypoxia-modifying measures implemented in the clinic are lacking.

adenocarcinoma
neutrophil count
metformin
serum pregnancy test
renal function
  • 0 views
  • 16 Feb, 2024
  • 1 location
Adaptative MR-Guided Stereotactic Body Radiotherapy of Liver Tumors

Hepatic metastases are common in solid cancers (up to 30% of patients with colorectal cancer and up to 50% of patients during their follow-up). The incidence of primary liver cancer increases due to the increase in chronic liver diseases induced by excessive alcohol consumption, hepatitis B and C viruses, and …

liver diseases
skin cancer
hepatitis
chelates
stereotactic radiation therapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of SGN-B6A in Advanced Solid Tumors

This trial will look at a drug called SGN-B6A to find out whether it is safe for people who have solid tumors. It will study SGN-B6A to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether …

cancer, ovarian
solid tumour
pancreatic adenocarcinoma
cancer of the ovary
ovarian ca
  • 0 views
  • 05 Aug, 2020
Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-na ve GBM Patients.

A multi-center, open-label, single-arm, phase I/II clinical study is designed to test the safety and immunogenicity of an investigational Dendritic and Glioma Cells Fusion vaccine given with IL-12 for treatment-nave patients after resection of glioblastoma.

white blood cell count
glioblastoma multiforme
blood cell count
temozolomide
glioma
  • 0 views
  • 05 Aug, 2020
Progressive Resistance Training for Sarcoma Survivors

This trial studies how well progressive resistance training works in improving the physical function of sarcoma survivors. Treatments for sarcoma can cause side effects such as fatigue, muscle loss, and weakness, which can negatively impact a patient's ability to physically function and enjoy an independent lifestyle. Engaging in a resistance …

residual tumor
resistance training
fatigue
cancer
sarcoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Trial Aiming to Assess the Safety and Activity of the Combination of Cabozantinib Plus Lanreotide in GEP and NET

A Phase II trial aiming to assess the safety and activity of the combination of cabozantinib plus lanreotide in gastroenteropancreatic (GEP) and thoracic neuroendocrine tumor (NET): The LOLA trial

corticosteroids
fridericia formula
clopidogrel
hepatic artery embolization
vegf
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Phase 1 Multi-Center Safety Dose Escalation Pharmacokinetics of INV-1120 in Adult Patients Advanced Solid Tumors

The safety, tolerability, and PK of INV-1120 will be assessed in adult patients with advanced solid tumors.

solid tumour
computed tomography
human chorionic gonadotropin
bone marrow procedure
MRI
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemotherapy.

metastatic head and neck squamous cell cancer
recurrent head and neck squamous cell carcinoma
metastatic head and neck squamous cell carcinoma
head and neck cancer
metastatic squamous cell carcinoma
  • 0 views
  • 05 Aug, 2020
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

endocrine therapy
solid tumour
fulvestrant
screening procedures
hormone therapy
  • 0 views
  • 16 Feb, 2024
  • 5 locations
Cemiplimab Before and After Surgery for the Treatment of High Risk Cutaneous Squamous Cell Cancer

This phase I trial studies how well cemiplimab before and after surgery works in treating patients with high risk cutaneous squamous cell cancer. Immunotherapy with monoclonal antibodies, such as cemiplimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow …

neutrophil count
extranodal extension
hypothyroidism
squamous cell carcinoma of the skin
primary lesion
  • 0 views
  • 05 Aug, 2020