Falls Church, Virginia Clinical Trials

A listing of Falls Church, Virginia clinical trials actively recruiting patient volunteers.

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Found 73 clinical trials
A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer

This study will evaluate the efficacy of tiragolumab plus atezolizumab and carboplatin and etoposide (CE) compared with placebo plus atezolizumab and CE in participants with chemotherapy-naive extensive-stage small cell lung cancer (ES-SCLC). Eligible participants will be randomized in a 1:1 ratio to receive one of the following treatment regimens during …

etoposide
measurable disease
atezolizumab
lung cancer
carboplatin
Virginia Cancer Specialists
 (4.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +146 other locations
A Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine Cyclophosphamide and Rituximab (FCR)/ Bendamustine And Rituximab (BR) in FIT Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without DEL (17P) or TP53 Mutation

This study will evaluate the efficacy and safety of venetoclax and obinutuzumab (VEN + G) compared with fludarabine + cyclophosphamide + rituximab or bendamustine + rituximab (FCR/BR) in FIT participants (FIT is defined by a cumulative illness rating scale [CIRS]/score of 6 and a normal creatinine clearance of 70 mL/min) …

bone marrow procedure
leukemia
platelet count
venetoclax
blood transfusion
Center For Cancer and Blood Disorders
 (7.5 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +50 other locations
Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy

This is a Phase III, multicenter, randomized, open-label study designed to evaluate the efficacy, safety, and pharmacokinetics of atezolizumab given in combination with cabozantinib compared with docetaxel monotherapy in patients with metastatic NSCLC, with no sensitizing EGFR mutation or ALK translocation, who have progressed following treatment with platinum-containing chemotherapy and …

atezolizumab
stage iv non-small cell lung cancer
cabozantinib
hepatitis b surface antigen
antibody test
Virginia Cancer Specialists (Fairfax) - USOR
 (4.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +97 other locations
A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

This study is being done to see if tucatinib with ado-trastuzumab emtansine (T-DM1) works better than T-DM1 alone to help patients who have a specific type of breast cancer called HER2 positive breast carcinoma. The breast cancer in this study is either metastatic (spread into other parts of the body) …

Virginia Cancer Specialists, PC
 (4.8 away) Contact site
  • 0 views
  • 14 Mar, 2022
  • +227 other locations
Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment (IMMPACTTest123)

The purpose of this research study is to look at the advantages of using a 3D printed heart model for surgical planning in children who have been diagnosed with Congenital Heart Disease (CHD) and clinical heart failure and will undergo a ventricular assist device (VAD) placement. The investigators want to …

Children's National Hospital
 (8.3 away) Contact site
  • 0 views
  • 28 Mar, 2024
  • +8 other locations
Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Background Diamond-Blackfan anemia (DBA) is treated with steroids. But some people cannot take steroids, or steroids don t work. Other patients must get blood transfusions regularly which are time consuming and can have significant side effects. The drug eltrombopag can increase red blood cells. Researchers want to see if it …

electrocardiogram
bone marrow erythroid
bone marrow biopsy
blood transfusion
cell counts
National Institutes of Health Clinical Center
 (9.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Background People with rare cancers often have limited treatment options. The biology of rare cancers is not well understood. Researchers want to find better treatments for these cancers. They want to test 2 drugs that, taken separately, have helped people with non-rare cancers. They want to see if these drugs …

carcinosarcoma
small intestine
epinephrine
metastasis
chordoma
National Institutes of Health Clinical Center
 (9.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Acalabrutinib Study With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19.

CALAVI US will investigate the safety, efficacy and pharmacokinetics of acalabrutinib together with Best Supportive Care in the treatment of COVID-19.

covid-19
acute respiratory syndrome (sars)
SARS
pneumonia
acalabrutinib
Research Site
 (9.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +9 other locations
A Study of LY3819253 (LY-CoV555) in Participants With Mild to Moderate COVID-19 Illness

The purpose of this study is to measure how well LY3819253 works against the virus that causes COVID-19. LY3819253 will be given to participants with early symptoms of COVID-19, via an injection into a vein. Samples will be taken from the back of the nose to determine how much virus …

hypertension
cardiovascular disease
gastrointestinal symptoms
lung disease
pharyngitis
CARE ID
 (4.0 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +61 other locations
Study to Evaluate the Safety and Efficacy of ATYR1923 In Patients With Severe Pneumonia Related to COVID-19

A Phase 2 study to evaluate the safety and preliminary efficacy of ATYR1923, compared to placebo, in hospitalized patients with SARS-CoV-2 (COVID-19) severe pneumonia not requiring mechanical ventilation

Inova Fairfax Medical Campus
 (1.9 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +4 other locations