Quincy, Massachusetts Clinical Trials

A listing of Quincy, Massachusetts clinical trials actively recruiting patient volunteers.

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Found 102 clinical trials
Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acute exacerbation of COPD usually presents with more sputum production leading to worsening airflow obstruction. Often patients complain of sensation of sputum (phlegm) stuck in throat, which leads to worsening cough and respiratory distress. In an acute exacerbation setting high flow nasal cannula (HFNC), which is a modality that provides …

pulmonary disease
acute exacerbation of chronic obstructive pulmonary disease
respiratory symptom
respiratory distress
respiratory symptoms
Tufts Medical Center
 (7.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Safety and Efficacy of 4 Investigational HSV 2 Vaccines in Adults With Recurrent Genital Herpes Caused by HSV 2

The primary objectives of the study are: To describe the safety profile of different investigational vaccine regimens against herpes simplex virus type 2 (HSV-2). To evaluate the efficacy of the investigational vaccine regimens with respect to: the frequency of herpes simplex virus (HSV) deoxyribonucleic acid (DNA) detection in the genital …

herpes simplex
recurrent genital herpes
western blot
antiviral
laboratory screening
Investigational Site Number 8400003
 (7.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
Pilot Study of the Haymakers for Hope Fitness Program

This research study is assessing the effect of an exercise program on cancer survivors. The exercise program is Haymakers for Hope 16-week exercise program

cancer diagnosis
melanoma
myocardial infarction
non-melanoma skin cancer
peripheral neuropathy
Massachusetts General Hospital Cancer Center
 (8.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
An Efficacy and Safety Study of Ravulizumab in ALS Participants

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

riluzole
vaccination
edaravone
ravulizumab
Massachusetts General Hospital
 (8.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +6 other locations
Genetic Testing for All Breast Cancer Patients (GET FACTS)

This study is designed to determine the impact of a novel genetic counseling method on surgical decisions in individuals with newly diagnosed breast cancer This research study involves an expedited and surgery-specific form of genetic counseling. The names of the study methods involved in this trial are/is: Quantitative genetic counseling …

breast carcinoma
cancer diagnosis
breast cancer
cancer
genetic testing
Dana Farber Cancer Institute
 (7.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Mechanism of Action of Transcranial Magnetic Stimulation

This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.

depressive episode
transcranial magnetic stimulation
psychiatric therapy
psychiatric treatment
depressive disorder
Massachusetts General Hospital
 (9.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

measurable disease
platelet count
tumor cells
primary peritoneal carcinoma
serum pregnancy test
Dana-Farber Cancer Institute
 (8.6 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
TDCS to Improve Motivation and Memory in Elderly (TIME)

Fundamental advancements in understanding successful aging are limited by the lack of causal, rather than just correlational methods to connect age-related changes in memory ability to changes in brain structure and function. In this study, non-invasive electric brain stimulation will be used as a tool to create causal links between …

Northeastern University
 (7.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy

Endocrine therapy is the initial treatment for most hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancers. This study will evaluate the use of venetoclax in combination with capecitabine in adult participants with HR+, HER2-, metastatic breast cancer (MBC) who had disease progression following treatment …

measurable disease
blood test
endocrine therapy
capecitabine tablets
hormone therapy
Massachusetts General Hospital /ID# 214833
 (8.7 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +15 other locations
Ibrutinib + Venetoclax in Untreated WM

This study evaluates the safety and efficacy of Ibrutinib combined with Venetoclax (IVEN) in the treatment of adults diagnosed with Waldenstrom's macroglobulinemia (WM) cancer with a specific MYD88 gene mutation. This research study involves an experimental drug combination of targeted therapies. The names of the study drugs involved in this …

venetoclax
plasmapheresis
measurable disease
waldenstrom's macroglobulinemia
myd88 gene mutation
Massachusetts General Hospital
 (8.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations