Houston, Louisiana Clinical Trials

A listing of Houston, Louisiana clinical trials actively recruiting patient volunteers.

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Found 98 clinical trials
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Study ASTX030-01 is designed to move efficiently from Phase 1 to Phase 3. Phase 1 consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (only one study drug will be escalated at a time) followed by a Dose …

immunosuppression
bone marrow procedure
chronic myeloid leukemia
chronic myelomonocytic leukemia
dysplasia
MD Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

This phase I/II trial studies the side effects and best dose of avelumab with M6620 in treating patients with deoxyribonucleic acid (DNA) damage repair (DDR) deficient solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). DDR deficiency refers to a …

FANCM
bone marrow suppression
HIV Infection
refractory malignant solid neoplasm
ovarian failure
M D Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

measurable disease
platelet count
tumor cells
primary peritoneal carcinoma
serum pregnancy test
University of Texas MD Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +3 other locations
Mind-Body Medicine for the Improvement of Quality of Life in Adolescents and Young Adults Coping With Hodgkin Lymphoma

This trial studies how well a mind-body intervention works in improving overall quality of life in adolescents and young adults with Hodgkin lymphoma. A meditation based mind-body intervention may help lower distress, depressive symptoms, and anxiety in adolescents and young adults coping with Hodgkin lymphoma.

anxiety
mind-body medicine
lymphoma
depressive symptoms
adult hodgkin lymphoma
M D Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

MRI
pleural effusion
bone marrow procedure
glomerular filtration rate
positron emission tomography
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +82 other locations
Use of an Educational Multimedia Tool Versus Routine Care for the Uptake of Postpartum LARC in High-Risk Pregnancies

The purpose of the study is to evaluate if the implementation of a multimedia based educational tool and regular reminders with shared decision-making will increase the rate of LARC uptake and retention in high risk pregnancy patients within 12 weeks of delivery and to study the rates of retention of …

high risk pregnancy
The University of Texas Health Science Center at Houston
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer

The purpose of this Phase I study is to determine the recommended phase 2 dose (RP2D) and safety profile of NBTXR3 activated by radiation therapy for the treatment of patients with pancreatic cancer that has spread to nearby tissues or lymph nodes (locally advanced) or may be able to be …

resectable pancreatic cancer
pancreatic cancer
platelet count
adenocarcinoma
irinotecan
M D Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults

Participants are being asked to participate in a research study conducted by Shih-Chiao Tseng, PT, Ph.D. at Texas Woman's University. This research study is to determine whether low-intensive brain stimulation can enhance learning of a leg movement task. The investigators also want to know if brain stimulation can improve the …

range of motion exercise
traumatic brain injury
chronic stroke
transcranial direct current stimulation
brain stimulation
Texas Woman's University
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of AK104 a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer

This is a Phase 2, global, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic cervical carcinoma.

bevacizumab
prednisone
pd-l1
cervical carcinoma
cancer treatment
Lyndon B. Johnson Hospital (MD Anderson)
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +19 other locations
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

This phase II trial studies how well acalabrutinib, lenalidomide, and rituximab work in treating patients with CD20 positive stage III-IV, grade 1-3a follicular lymphoma. Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as lenalidomide, work …

follicular large cell lymphoma
prothrombin
aptt
bone marrow procedure
positron emission tomography
M D Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location