Ville Saint-Laurent, Canada Clinical Trials

A listing of Ville Saint-Laurent, Canada clinical trials actively recruiting patients volunteers.

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Found 52 clinical trials
An Efficacy and Safety Study of Ravulizumab in ALS Participants

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

riluzole
vaccination
edaravone
ravulizumab
Montreal Neurological Institute and Hospital
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +6 other locations
Postop Hypofractionated Radiation Therapy and LHRH in Patients With Prostate Cancer

Prostate cancer is the second most common cancer among Canadian men of which approximately 20-30% present with high-risk tumour characteristic. Although surgery can be curative in patients evidencing pathological high-risk disease (extracapsular extension, seminal vesicle involvement, positive surgical margins), a large proportion will develop biochemical failure within years from the …

MRI
digital rectal exam
lymphadenectomy
hypofractionated radiation therapy
prostate specific antigen
McGill University Health Centre- Cedars Cancer Centre
 (7.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
An Adaptive Dyadic Self-directed Coping and Self-management Skills Training Intervention for Caregivers of Individuals With Cancer

High-quality cancer care in Canada relies on family caregivers. Since cancer treatment is provided more and more in outpatient clinics, family caregivers now provide most of the support and care patients need when they return home. The problem is that caregivers often do not feel they have the knowledge and …

cancer diagnosis
colorectal cancer
motivational interviewing
cancer therapy
anxiety
St Mary's Hospital Centre
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as definitive treatment. Current treatment of oropharyngeal cancer are chemo-radiotherapy. There is significant lifelong side effects associated with this approach related to …

oropharyngeal cancer
absolute neutrophil count
neck dissection
docetaxel
karnofsky performance status
McGill University Health Centre
 (7.4 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • 1 location
Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning?

Age-related vision impairment and dementia both become more prevalent with increasing age. Research into the mechanisms of these conditions has proposed that some of their causes (e.g., macular degeneration/glaucoma and Alzheimer's disease) could be symptoms of an underlying common cause, or may be equally linked to a multifactorial context in …

macular degeneration
deafness
alzheimer's disease
visual impairment
reading rehabilitation
Centre de r adaptation Lethbridge-Layton-Mackay du CIUSSS du Centre-Ouest-de-l' le-de-Montr al
 (6.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +1 other locations
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

kras
ki-ras
kras g12c mutation
solid tumour
metastatic malignant solid tumor
Jewish General Hospital; Sir Mortimer B. Davis
 (8.2 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +7 other locations
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

combination therapy
taxane
prostatic neoplasms, castration-resistant
antiandrogen therapy
prostatic neoplasm
Centre hospitalier de l'Universit de Montr al (CHUM) Centre de Recherche
 (9.3 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +21 other locations
PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes, and imaging, biologic and genetic markers of Parkinson's disease (PD) progression in study participants with manifest PD, prodromal PD, and healthy controls The overall goal of …

modafinil
genetic testing
methyldopa
resting tremor
datscan
McGill University
 (8.1 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +45 other locations
Pompe Disease Registry

The Pompe Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Pompe disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The objectives …

deficiency
glycogen storage disease type ii
gaa gene
myozyme
replacement therapy
Investigational Site Number 124004
 (8.1 away) Contact site
  • 0 views
  • 22 Dec, 2020
  • +168 other locations
Cell-free DNA in Hereditary And High-Risk Malignancies

The goal of this study is to develop an effective, sensitive blood test that can detect early tumours in patients with known or suspected hereditary cancer syndromes (HCS). If this new blood test is accurate, it could be used to screen patients for cancer and allow for earlier cancer detection. …

hereditary cancer
blood test
cell-free dna
cancer
hereditary cancer syndromes
Jewish General Hospital
 (5.8 away) Contact site
  • 0 views
  • 16 Feb, 2024
  • +6 other locations