a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 2490 clinical trials
A Study to Evaluate the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of CN1

This study is the first-in-human clinical trial of CN1 to evaluate the safety, tolerability, pharmacokinetic (PK) profile and preliminary efficacy of CN1 in patients with advanced solid tumors or B-cell lymphoma. This study will provide a basis for further clinical development of CN1.

lymphoma
solid tumour
b-cell lymphoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis

This trial is part of the chronic pain master protocol (H0P-MC-CPMP) which is a protocol to accelerate the development of new treatments for chronic pain.

chronic pain
x-rays
knee pain
osteoarthritis
body mass index
  • 0 views
  • 05 Aug, 2020
A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer

This study will evaluate the safety, tolerability, and pharmacokinetics of BLYG8824A and will make a preliminary assessment of the anti-tumor activity of BLYG8824A in patients with locally advanced or metastatic colorectal cancer.

fluoropyrimidine
combination therapy
measurable disease
solid tumour
oxaliplatin
  • 0 views
  • 05 Aug, 2020
Sujana-A Phase 1/Phase 2 open-label study to evaluate the safety, tolerability, and efficacy of a single intravenous administration of an investigational medication in adult participants with phenylketonuria (PKU)  

If you are interested in learning more about this study, we encourage you to complete a briefquestionnaire to help determine if you may qualify to participate and be referred to a siterecruiting in your area for further evaluation.

  • 0 views
  • 13 Nov, 2023
  • 1 location
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)

It is known that people with ILD are highly inactive and sedentary, and in a severe stage of the disease, these people spend most of the time at home, increasing dependency on others, and decrease HRQoL. Physical activity is a cost-effective intervention, which increases the HRQoL, exercise capacity and ability …

  • 0 views
  • 16 Feb, 2024
  • 1 location
Development and Evaluation of a Web Based Decision Aid for Patients With Hip Osteoarthritis

The main goal of this study is assess the effectiveness of a PtDA for patients with hip osteoarthritis

osteoarthritis of hip
osteoarthritis
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Study ASTX030-01 is designed to move efficiently from Phase 1 to Phase 3. Phase 1 consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (only one study drug will be escalated at a time) followed by a Dose …

myelodysplastic/myeloproliferative disease
leukemia
cytotoxic chemotherapy
myeloid leukemia
myelodysplastic syndrome
  • 0 views
  • 16 Feb, 2024
  • 2 locations
A Multicentre Non-Blinded Study Exploring Self-Administration of Chemotherapy in the Home Environment

This study is to see if the standard of care subcutaneous injection of bortezomib can safely be administered at home by the patient or caregiver. All tests and assessments are based on standard of care procedures.

cancer
multiple myeloma
bortezomib
  • 0 views
  • 16 Feb, 2024
  • 1 location
Altered Tumor Oxygenation by Metformin a Potential Step in Overcoming Radiotherapy Resistance in LACC

This study is a randomized, phase II, open label study in patients with LACC where patients are randomized to standard cisplatin-based chemoradiotherapy +/- Metformin.

cisplatin
blood transfusion
cervical neoplasm
carcinoma
adenocarcinoma
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Assess Safety Tolerability and Pharmacokinetics of ABI-H3733 in Healthy Adults

Part 1 includes evaluation of the safety, tolerability, and PK of ABI-H3733 during single ascending dose (SAD) and multiple-ascending dose (MAD) administration of the oral liquid formulation. Part 2 includes assessment of a solid dosage formulation of ABI-H3733 in participants under fasted conditions or after a high-fat meal. Optional cohorts …

  • 0 views
  • 16 Feb, 2024
  • 1 location