a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 2490 clinical trials
The Study of IBI310 in Combination With IBI308 Compared to High-Dose Interferon In Patients With Acral Melanoma That Has Been Removed by Surgery

This is a phase III randomized, control, multi-center study of recombinant humanized anti-PD-1 mAb in combination with CTLA4 mAb for injection compared to high-Dose interferon in patients with acral melanoma that has been removed by surgery.

  • 0 views
  • 16 Feb, 2024
  • 1 location
Clinical High and Genomic Low Hormone Receptor-positive Early Breast Cancer Patients With or Without Adjuvant Chemotherapy

A prospective, randomized, comparative study to evaluate efficacy of anticancer chemotherapy in predicting prognosis and determining chemotherapy method in early Hormone Receptor-positive breast cancer patients with clinicopathological high risk and GenesWell BCT low risk at multi-center in Korea

  • 0 views
  • 16 Feb, 2024
  • 1 location
Safety Tolerability Pharmacokinetics and Antitumor Activity of FCN-437c

This is a multicenter, open, single arm dose escalation and dose expansion clinical study to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of FCN-437c alone or in combination with letrozole in women with ER +/ HER2 - advanced breast cancer.

measurable disease
advanced breast cancer
breast cancer
hormone therapy
metastasis
  • 0 views
  • 16 Feb, 2024
  • 1 location
Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients

This Phase 1 single-dose, dose-escalation study is an open label trial evaluating the safety of CPI-006, a humanized monoclonal antibody targeting the CD73 cell-surface ectonucleotidase, as immunotherapy for stable hospitalized mild or moderately symptomatic COVID-19 patients.

monoclonal antibodies
nasopharyngeal swab
covid-19
acute respiratory syndrome (sars)
cancer
  • 0 views
  • 05 Aug, 2020
PAXG Out in the Country

The objective of this study is to assess the reproducibility of PAXG regimen as first-line/primary chemotherapy in daily clinical practice in Pancreatic Ductal Adenocarcinoma (PDAC) borderline resectable, locally advanced or metastatic patients out of a large volume center.

gemcitabine
metastasis
cisplatin
ductal adenocarcinoma
pdac
  • 0 views
  • 05 Aug, 2020
Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT

There is however often poor tumour control with this technique due to the low doses given. Stereotactic Radiosurgery (SRS), a form of focused radiotherapy which is given to patients who have a limited number of brain metastases, gives a higher radiation dose to the metastases resulting in better target lesion …

stereotactic radiosurgery
metastasis
hydrocephalus
primary malignant neoplasm
serum pregnancy test
  • 0 views
  • 16 Feb, 2024
  • 1 location
Targeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276

This study attempts to treat these diseases using T cells genetically modified with a 4th generation lentiviral chimeric antigen receptor (4SCAR fused with an inducible apoptotic caspase 9 domain) targeting CD276 (B7-H3).

immunohistochemistry
antibody therapy
monoclonal antibodies
ejection fraction
blood transfusion
  • 0 views
  • 16 Feb, 2024
  • 3 locations
checkbox

This is a randomized, open-label, parallel group study to determine the optimal dose of CART-19 cells (of the two dose levels being assessed (1-5x10xE8 vs. 1-5x10xE7 CART-19 cells).

  • 0 views
  • 23 Feb, 2023
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This is a randomized, open-label, parallel group study to determine the optimal dose of CART-19 cells (of the two dose levels being assessed (1-5x10xE8 vs. 1-5x10xE7 CART-19 cells).

  • 0 views
  • 23 Feb, 2023
Transcranial Direct Current Stimulation for Impulsivity and Food-related Impulsivity in Obesity

In this study the investigators aim to assess whether transcranial direct current stimulation (tDCS; a safe non-invasive method for modulating the activity of specific brain regions) when applied over the orbitofrontal cortex (OFC) is able to modulate impulsivity in obese participants.

transcranial direct current stimulation
body mass index
  • 0 views
  • 16 Feb, 2024
  • 1 location