a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 2490 clinical trials
Safety Tolerability and Immunogenicinity of a Coronavirus-Like Particle COVID-19 Vaccine in Adults Aged 18-55 Years.

The same process will be followed for the second vaccine administration. All subjects will be followed for a period of six months after the second administration of the vaccine for safety and immunogenicity testing at the end of the follow-up period.

SARS
body mass index
acute respiratory syndrome (sars)
hormonal contraception
hysterectomy
  • 0 views
  • 01 Feb, 2023
  • 2 locations
A Study to Evaluate OP-101 (Dendrimer N-acetyl-cysteine) in Severe Coronavirus Disease 2019 (COVID-19) Patients

The primary purpose is to evaluate the safety and tolerability of OP-101 and secondary purpose is to determine the effect of OP-101 reducing proinflammatory cytokines after a single dose in severe COVID-19 Patients.

SARS
respiratory distress
acute respiratory distress
cytokines
respiratory tract infection
  • 0 views
  • 05 Aug, 2020
A Safety Tolerability and Efficacy of EIDD-2801 to Eliminate Infectious Virus Detection in Persons With COVID-19

This is a phase IIa, double-blind, placebo-controlled, randomized trial, designed to compare the safety, tolerability, and antiviral activity of EIDD-2801 versus placebo as measured by infectious virus detection in symptomatic adult outpatients with COVID-19

chills
dyspnea
anosmia
acute respiratory syndrome (sars)
estrogen
  • 0 views
  • 01 Feb, 2023
  • 1 location
Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label Study (TOPAMAD)

This study has been planned to compare the efficacy and tolerability of topiramate, a commonly used second line agent, with modified Atkins diet in children with epileptic spasms refractory to hormonal treatment, in a randomized open label study.

  • 0 views
  • 25 Jul, 2023
  • 1 location
A Randomized Comparison of Transobturator Tape With the Plication of Urethral Ligaments in the Treatment of Stress Urinary Incontinence (added)

The goal of this clinical trial is to compare the efficacy of transobturator tape (TOT) operation and urethral ligament plication operation in stress incontinence patients. The main question: - Which operation is more effective in treatment of stress incontinence? - Which operation has less complication and risks? Participants will be …

  • 0 views
  • 30 Jan, 2024
  • 1 location
A Randomized Comparison of Transobturator Tape With the Plication of Urethral Ligaments in the Treatment of Stress Urinary Incontinence (added)

The goal of this clinical trial is to compare the efficacy of transobturator tape (TOT) operation and urethral ligament plication operation in stress incontinence patients. The main question Which operation is more effective in treatment of stress incontinence? Which operation has less complication and risks? Participants will be followed about …

  • 0 views
  • 31 Jan, 2024
  • 1 location
A Study of IBI377 in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

The purpose of this study is to evaluate itacitinib in combination with corticosteroids as first-line treatment of participants with Grade II to IV acute graft-versus-host disease (aGVHD).

acute graft versus host disease
corticosteroids
graft versus host disease
stem cell transplantation
hematologic malignancy
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of HMPL-306 in Patients With IDH1 and/or IDH2 Mutation of Relapsed/Refractory Myeloid Leukemia/Neoplasms

Phase I, multicenter study to evaluate the safety, pharmacokinetics, pharmacodynamics and efficacy of HMPL-306 in Patients of Relapsed/Refractory Myeloid Leukemia/Neoplasms with IDH1 and/or IDH2 Mutation.

myeloid neoplasm
chronic myelomonocytic leukemia
leukemia
idh2 gene mutation
myelodysplastic syndromes
  • 0 views
  • 16 Feb, 2024
  • 1 location
Markers to Evaluate the Efficacy of PH-based Regimen as a Neoadjuvant Therapy for Operable HER2 Positive Breast Cancer

This study is to explore the markers in early prediction of the efficacy of pre-operative pertuzumab plus trastuzumab (PH) combined with chemotherapy for early stage or locally advanced human epidermal growth factor receptor-2 (HER-2) positive primary breast cancer.

pertuzumab
her1
core needle biopsy
growth factor
her-2
  • 0 views
  • 16 Feb, 2024
  • 1 location
Comparing the Efficacy and Safety of a New Additional Treatment With Tislelizumab in Non-Small Cell Lung Cancer (NSCLC)

The primary objective of this study is to evaluate and compare major pathological response(MPR) rate and event-free survival (EFS) in participants receiving tislelizumab plus platinum-based doublet chemotherapy as the new additional treatment followed by tislelizumab as adjuvant treatment versus participants receiving placebo plus platinum-based doublet chemotherapy as neoadjuvant treatment followed …

immunomodulators
pemetrexed
measurable disease
lung cancer
adjuvant
  • 0 views
  • 16 Feb, 2024
  • 41 locations