a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 2490 clinical trials
A RCT - Safety & Efficacy of Tocilizumab - Tx of Severe COVID-19: ARCHITECTS

The overall objective is to evaluate the clinical efficacy and safety of tocilizumab relative to placebo among approximately 300 hospitalized adult patients who have severe COVID-19. The study will be a 2 arm double blinded comparison between tocilizumab 8 mg/kg and matching placebo IV. The dose may be repeated in …

shock
ct scan
vasopressor
respiratory distress
vasoconstrictor
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study to Evaluate the Tolerance Efficacy and Pharmacokinetics of TQB3558 Tablets

This is a study to evaluate the maximum tolerated dose (MTD) , occurrence of all adverse events (AE) and serious adverse events (SAE) , pharmacokinetic parameters and antitumor effect of TQB3558 tablets in Chinese adult patients with advanced solid tumors .The study is divided into phase Ia and phase Ib.

  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study of SBT6050 in Patients With Advanced HER2 Expressing Solid Tumors

A first-in-human (FIH) study using SBT6050 in HER2 expressing advanced malignancies

measurable disease
solid tumor
cancer
pembrolizumab
solid tumour
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Effect of LPEC Compared With a Sham Procedure in the General Anesthesia

Check the condition of intubation with LPEC compared with a sham procedure in the general anesthesia

intubation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Evaluation of a Oncology Day Care Unit Programme With Two Different Focuses

The aim of this study is to investigate the effects of a nature-centred integrative oncology day care unit programme ("outdoor concept") compared with an already established integrative oncology day care unit programme ("indoor concept").

cancer
cancer diagnosis
  • 0 views
  • 05 Aug, 2020
A Trial of Neoadjuvant mXELOXIRI Versus CRT in the EMVI Positive LARC

Extramural Vascular Invasion Positive(EMVI+) is a high risk of distant metastasis for locally advanced rectal cancer(LARC) after resection. The study is to evaluate the efficacy and safety of XELOXIRI as neoadjuvant chemotherapy alone for EMVI+ LARC in contrast to the efficacy of standard Chemoradiotherapy (CRT).

rectal carcinoma
cancer
metastasis
renal function
platelet count
  • 0 views
  • 05 Aug, 2020
A Study of Surufatinib Plus Sintilimab in Patients With Advanced Solid Tumor

The purpose of this study is to evaluate the safety and efficacy of Surufatinib plus Sintilimab in Patients with Advanced Solid Tumor

  • 0 views
  • 05 Aug, 2020
A Study to Evaluate the Tolerance Pharmacokinetics and Efficacy of TQ-A3334 Tablets

This is a study to evaluate the tolerance, dose-limiting toxicity (DLT), and maximum tolerated dose (MTD) of single and multiple oral doses of TQ-A3334 and observe the efficacy of TQ-A3334 in combination with anlotinib capsules in patients with non-small cell lung cancer.

measurable disease
EGFR
lung cancer
anlotinib
cancer
  • 0 views
  • 16 Feb, 2024
  • 1 location
A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease

This is a non-randomized, open-label, multi-site, single-dose, Phase 3 study in approximately 35 adults and pediatric subjects 2 and 50 years of age with sickle cell disease (SCD).

analgesia
priapism
pediatric
karnofsky performance status
gene therapy
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Clinical Feasibility of Minimally Supervised Therapy After Stroke With a Hand Rehabilitation Robot

The ReHapticKnob is a robot for hand rehabilitation after stroke. We aim to investigate the feasibility of minimally supervised therapy with the ReHapticKnob with stroke patients in a rehabilitation clinic, evaluate the usability of the ReHapticKnob (user interface and implemented exercises which were adapted for independent usage), and quantify the …

ataxia
  • 0 views
  • 16 Feb, 2024
  • 1 location