a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 2490 clinical trials
Blood Pressure Management on Cardiovascular AdveRse Events After Major Abdominal Surgery

This study is a multicenter randomized controlled trial comparing an intensive intraoperative blood pressure management strategy versus conventional practice for preventing cardiovascular events in high-risk patients undergoing major abdominal surgery.

hypertension
stroke
blood pressure management
coronary artery disease
heart failure
  • 0 views
  • 16 Feb, 2024
  • 3 locations
Smart Discharges to Improve Post-discharge Health Outcomes in Children

In Uganda, about 5% of children discharged after hospitalization for a serious infection will die in the weeks after returning home. Doctors and parents are often unaware of this period of vulnerability and are poorly equipped to identify or handle this critical situation.

  • 0 views
  • 16 Feb, 2023
  • 1 location
Clinical Study for Treatment-naïve IOPD Babies to Evaluate Efficacy and Safety of ERT With Avalglucosidase Alfa (Baby-COMET)

This is a single group, treatment, Phase 3, open-label study to assess efficacy, safety, pharmacokinetic (PK), pharmacodynamics (PD) of avalglucosidase alfa in treatment-naïve male and female participants with IOPD.

  • 0 views
  • 19 Jul, 2024
  • 4 locations
Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19

This study is a randomized, double-blinded, and placebo-controlled phase Ia/IIa clinical trial of the Inactivated SARS-CoV-2 Vaccine to evaluate the safety and immunogenicity of the vaccine in healthy people aged 18~59 Years.

acute respiratory syndrome (sars)
covid-19
SARS
  • 0 views
  • 16 Feb, 2024
  • 1 location
Supramarginal Resection in Glioblastoma

There are now several case series, using various definitions of supramarginal resection, but they have in common that they report a benefit of resection with a margin. This potential benefit also comes together with an associated neurological risk, making this approach unethical and simply not feasible in the patients with …

astrocytoma
supratentorial glioblastoma
malignant glioma
glioblastoma multiforme
malignant brain tumor
  • 0 views
  • 16 Feb, 2024
  • 19 locations
High Risk ER+HER2- T1-2N0-1 Early Breast Cancer With Palbociclib Plus Endocrine Therapy(HIPEx)

This is a phase II, multi-center, single-arm, open-label trial to evaluate efficacy of palbociclib with endocrine therapy as adjuvant treatment in women with C-high/G-high risk ER-positive/HER2-negative T1-2N0-1 EBC(Early Breast Cancer)

her2-negative breast cancer
formalin-fixed paraffin-embedded
her2/neu-negative breast cancer
invasive breast cancer
breast cancer 3
  • 0 views
  • 16 Feb, 2024
  • 1 location
Randomised Evaluation of COVID-19 Therapy (RECOVERY)  

RECOVERY is a randomised trial investigating whether treatment with Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin, Colchicine, IV Immunoglobulin (children only), Convalescent plasma, Casirivimab+Imdevimab, Tocilizumab, Aspirin, Baricitinib, Infliximab, Empagliflozin, Sotrovimab, Molnupiravir, Paxlovid or Anakinra (children only) prevents death in patients with COVID-19.

  • 0 views
  • 14 Sep, 2022
  • 6 locations
Study to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell Disease

This study is a Phase 3, randomized, double-blind, placebo-controlled study of voxelotor in pediatric participants, aged 2 to < 15 years old, with Sickle Cell Disease.

cerebral blood flow
voxelotor
gbt440
pediatric
transcranial doppler ultrasonography
  • 0 views
  • 16 Feb, 2024
  • 35 locations
Study in Subjects With Relapsed/Refractory Follicular Lymphoma

This is a multicenter, double-blind, active-controlled, randomized, 3-stage, biomarker enrichment design featuring early futility stopping and sample-size re-estimation with safety run-in designed to evaluate the efficacy and safety of tazemetostat in combination with R2 in subjects with R/R FL, who have completed at least 1 prior systemic chemotherapy, immunotherapy, or …

cancer therapy
bone marrow procedure
investigational treatment
tositumomab
systemic chemotherapy
  • 0 views
  • 16 Feb, 2024
  • 8 locations
Controlled Ovarian Stimulation in Newly Diagnosed Breast Cancer PatiEnts (fAMHOPE)

This is a multicenter hospital-based prospective cohort study conducted in institutions with known expertise in performing oocytes/embryo freezing for fertility preservation.

breast neoplasm
letrozole
breast carcinoma
cancer
adjuvant chemotherapy
  • 0 views
  • 16 Feb, 2024
  • 4 locations