a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 2490 clinical trials
Non-invasive Stroke Volume-based uid Management in Elderly Patients Undergoing Hip Fracture Surgery Under Spinal Anaesthesia

The study is going to be a single-centre prospective randomized trial. Patients will be randomly allocated to either control group (anesthetist-directed fluid therapy) or goal directed fluid therapy group, in which fluid therapy was guided by stoke volume (SV) algorithm with the use of Nexfin monitor.

fluid therapy
anesthesia
hypotensive
stroke
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Intervening With Opioid-Dependent MothersMothers and Infants

The investigators expect that mothers who receive the modified Attachment and Biobehavioral Catch-up Intervention will show more nurturing and sensitive parenting and more adaptive physiological regulation than parents who receive a control intervention. The investigators expect that infants whose mothers receive the modified Attachment and Biobehavioral Catch-up will show better …

opioid use disorder
opioid
narcotic use
  • 0 views
  • 16 Feb, 2024
  • 1 location
An Advance Care Planning Programme for Persons With Early Stage Dementia or Mild Cognitive Impairment in the Community

This proposed study attempts to promote the uptake of ACP for this population and their family caregivers in the community and to examine the effects of an ACP programme "Have a Say" for this population. It is hypothesized that participants in the intervention group will be more engaged in ACP …

cognitive impairment
dementia
mild cognitive impairment
  • 0 views
  • 16 Feb, 2024
  • 4 locations
Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery

This study aimed to determine the impact of an Enhanced Recovery Surgery pathway on short- term and long- term results in patients undergoing lung resection for primary lung cancer. Methods: A Randomized Controlled Trial was designed to collect the perioperative data on consecutive patients undergoing lung resection for primary lung …

pulmonary resection
lung operation
enhanced recovery after surgery
cancer
lung surgery
  • 18 views
  • 05 Aug, 2020
18F-DCFPyL PET/CT Impact on Treatment Strategies for Patients With Prostate Cancer

The main purpose of this phase II trial study is to determine whether a positron emission tomography (PET)/computed tomography (CT) scan using 18F-DCFPyL affects the clinical management plan in Veterans.

prostatectomy
prostate cancer metastatic
positron emission tomography
metastatic prostate cancer
external beam radiation therapy
  • 0 views
  • 05 Aug, 2020
Interactive Decision Aid for Men Diagnosed With Prostate Cancer

The SC group will meet with their urologist and receive and information brochure. In addition the IDA group will receive a website that includes a wealth of information (e.g., overview about prostate cancer, overview of different treatment options, pros and cons of different treatment options and a value clarification exercise …

cancer diagnosis
  • 0 views
  • 16 Feb, 2024
  • 1 location
NBTXR3 Activated by Radiation Therapy for the Treatment of Locally Advanced or Borderline-Resectable Pancreatic Cancer

The purpose of this Phase I study is to determine the recommended phase 2 dose (RP2D) and safety profile of NBTXR3 activated by radiation therapy for the treatment of patients with pancreatic cancer that has spread to nearby tissues or lymph nodes (locally advanced) or may be able to be …

cisplatin
resectable pancreatic cancer
capecitabine
adenocarcinoma
fluorouracil
  • 0 views
  • 16 Feb, 2024
  • 1 location
Feasibility and Effectiveness of Delivering Cognitive Behaviour Therapy Through Online Psychotherapy Tool (OPTT) for Depression

To the principal investigators' knowledge, this study will be the first multi-site study examining the efficacy of e-CBT in depression compared to pharmacotherapy using a naturalistic research design.

depressive disorder
psychiatric disorder
major depressive disorder
anxiety
psychotherapy
  • 0 views
  • 16 Feb, 2024
  • 1 location
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

Drugs used in chemotherapy, such as lenalidomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Rituximab is a monoclonal antibody that may interfere with the ability of cancer cells to grow …

growth factor
grade 2 follicular lymphoma
international normalized ratio
stage iv grade 1 follicular lymphoma
aptt
  • 0 views
  • 16 Feb, 2024
  • 1 location
Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)

This study is designed to assess the safety and efficacy of lenvatinib in combination with pembrolizumab versus standard of care (SOC) chemotherapy, and to also assess the safety and efficacy of lenvatinib monotherapy in participants with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) that have progressed after platinum …

cisplatin
docetaxel
pembrolizumab
carcinoma
mk-3475
  • 0 views
  • 16 Feb, 2024
  • 3 locations