a, a N Clinical Trials
A listing of a, a N clinical trials actively recruiting patients volunteers.
Found 2490 clinical trials
INDV-2000 First in Human
This study will be a single ascending dose (SAD) study conducted to identify the maximum tolerated dose (MTD). After completion of the SAD portion of the study and acceptable safety evaluation, a food-interaction, single-dose study under fed and fasted conditions will be conducted.
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- 16 Feb, 2024
- 1 location
The Effect of Acupressure on Fatigue in Individuals With Chronic Fatigue Syndrome
Chronic fatigue syndrome is a common problem in society. The treatment of this problem is limited. Acupressure is a treatment method that has become widespread and promising in recent years.
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- 05 Aug, 2020
Remote Ischemic Conditioning to Enhance Resuscitation (RICE) Pilot
Remote ischemic conditioning (RIC) consists of intermittent application of a device such as a blood pressure cuff to a limb to induce non-lethal ischemia. Studies in animals with cardiac arrest as well as in humans with acute myocardial infarction suggest that RIC before or after restoration of blood flow may …
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- 16 Feb, 2024
- 1 location
Does Insulin Sensitivity Impact the Potential of Metformin to Slow Aging
After consent and initial subject screening for chronic disease, subjects will be stratified to insulin sensitive (IS) or insulin resistant (IR) groups. Over a 12- week intervention, half of each group will take metformin and half will take a placebo. Pre- and post--intervention, subjects will complete a series of procedures …
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- 16 Feb, 2024
- 2 locations
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma
Primary Objectives: Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B Dose Expansion Part B: To assess the …
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- 04 Dec, 2020
- 8 locations
ABC Study - Diabetes Study Trial
A randomized clinicial trial assessing the efficacy of _
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- 25 Apr, 2025
- 1 location
Acceptance and Commitment Therapy-based Eczema Management Programme (ACTeczema)
This pilot randomised wait-list controlled trial aims to determine the feasibility, acceptability and preliminary effects of a Family Acceptance and Commitment Therapy-based Eczema Management Programme (FACT-EMP) on the health outcomes of both children patients and their main caregivers over a 3-month post-intervention.
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- 16 Jan, 2024
- 1 location
First-in-Human Dose Escalation Trial of ATRC-101 in Adults With Advanced Solid Malignancies
ATRC-101-A01 is a first-in-human, Phase 1b, open-label trial to characterize the safety, tolerability, pharmacokinetics (PK), and biological activity of escalating doses of ATRC-101, an engineered, fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally-occurring human antibody.
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- 16 Feb, 2024
- 1 location
Mind-Body Medicine for the Improvement of Quality of Life in Adolescents and Young Adults Coping With Hodgkin Lymphoma
This trial studies how well a mind-body intervention works in improving overall quality of life in adolescents and young adults with Hodgkin lymphoma. A meditation based mind-body intervention may help lower distress, depressive symptoms, and anxiety in adolescents and young adults coping with Hodgkin lymphoma.
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- 16 Feb, 2024
- 1 location
OTL-200 in Patients With Late Juvenile Metachromatic Leukodystrophy (MLD)
OTL-200 is a cryopreserved dispersion for infusion containing autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene.
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- 16 Feb, 2024
- 1 location