Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 953 clinical trials
Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Acute exacerbation of COPD usually presents with more sputum production leading to worsening airflow obstruction. Often patients complain of sensation of sputum (phlegm) stuck in throat, which leads to worsening cough and respiratory distress. In an acute exacerbation setting high flow nasal cannula (HFNC), which is a modality that provides …

dyspnea
pulmonary disease
cough
respiratory distress
respiratory symptoms
  • 0 views
  • 16 Feb, 2024
  • 1 location
Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery

Objective: The adoption of Enhanced Recovery Surgery programs in lung resection is relatively recent with limited outcome data. This study aimed to determine the impact of an Enhanced Recovery Surgery pathway on short- term and long- term results in patients undergoing lung resection for primary lung cancer.

enhanced recovery after surgery
lung surgery
cancer
lung cancer
pulmonary resection
  • 18 views
  • 05 Aug, 2020
Selfcare MAnagement InteRvenTion in COPD (SMART COPD)

To evaluate whether a digital support and communication platform for COPD patients after 6 months provides: Decreased breathlessness on the basis of modified medical research council dyspnea scale [mMRC] Improved health status and symptom relief based on COPD assessment scale [CAT] Improved quality of life based on EQ-5D Reduction in …

dyspnea
  • 0 views
  • 05 Aug, 2020
Quality-of-Life Management for COPD Patients

The investigators aim to investigate the effects of a telemonitoring and chatbot-based application of "Living well with COPD" (CAir) on health-related quality-of-life in patients with COPD.

  • 0 views
  • 05 Aug, 2020
Lorlatinib Combinations in Lung Cancer

This research study is evaluating Lorlatinib in combination with Crizotinib or Binimetinib as a possible treatment for either anaplastic lymphoma kinase (ALK)-positive lung cancer or ROS1-positive lung cancer. This research study involves three study drugs. Lorlatinib Binimetinib Crizotinib

prophylaxis
levetiracetam
non-small cell lung cancer
ascites
lorlatinib
  • 0 views
  • 16 Feb, 2024
  • 2 locations
Doxapram Therapy in Preterm Infants (DOXA Trial)

This study compares doxapram to placebo and hypothesizes that doxapram will protect preterm infants from both invasive ventilation (and related lung disease) and AOP related oxygen shortage (and related impaired brain development).

off-label
pulmonary disease
doxapram
apnea
mechanical ventilation
  • 0 views
  • 16 Feb, 2024
  • 18 locations
Clinical Utility of Liquid Biopsy in Brigatinib ALK+ Patients

Chemotherapy-nave patients with EML4-ALK rearrangement and with locally advanced or metastatic non-small cell lung cancer patients will be selected. Patients enrolled in the study will receive brigatinib 90mg for the first 7 days (D 1-7 at cycle 1) and then 180mg daily thereafter for QW4 cycles of duration (28 days …

blood transfusion
hepatitis
bone metastases
non-small cell lung cancer
adjuvant chemotherapy
  • 0 views
  • 16 Feb, 2024
  • 15 locations
SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions

Prospective phase I study to evaluate the maximum tolerated dose (MTD) of SBRT for thoracic re-irradiation. Dose limiting toxicity will be pneumonitis G3. The potential advantage of the dose escalation planned in this study is the delivery of an ablative dose to radically treat patients with inoperable local relapse, without …

pneumonitis
stereotactic body radiation therapy
non-small cell lung cancer
small cell lung cancer
reirradiation
  • 0 views
  • 16 Feb, 2024
  • 1 location
Monitoring COVID-19 Patients' Lung Fluid Using Impedance Technique

Today, a chest X-ray is the only practical way to check the degree of lung accumulation. However, X-Ray has many limitations and disadvantages. Lung impedance technology allows simple lung fluid monitoring, and found to be effective in HF patients who suffer from a similar problem.

respiratory distress
chest x-ray
covid-19
x-rays
acute respiratory distress
  • 0 views
  • 05 Aug, 2020
Lung Ultrasound Assessment of Fluid Overload in Haemodialysis Patients (EP8SH)

It can estimate pulmonary congestion. The aim of the study is to evaluate the lung ultrasound using "8 sites" score accuracy for estimating fluid overload of patients before hemodialysis session.

  • 0 views
  • 24 Nov, 2021
  • 1 location