Overview
The study is devoted to the comparative analysis of the data received in patients with COVID-19 lung pathology using the method of probe-based confocal laser endomicroscopy of distal airways and two reference methods: high resolution computed tomography and morphology (in some patients).
Eligibility
Inclusion Criteria:
- Patient Informed Consent;
- the diagnosis of COVID-19 or one of the following lung diseases: chronic obstructive pulmonary disease, pneumonia, solitary nodule, pulmonary sarcoidosis, idiopathic interstitial pneumonia, hypersensitivity pneumonitis, pulmonary vasculitis, pulmonary eosinophilia, hemochromatosis, histiocytosis X, pulmonary lymphangioleiomyomatosis; alveolar proteinosis, other rare lung disease
- high resolution computed tomography scans performed not later than one month before pCLE (for non-COVID-19);
- planned or performed histology (for non-COVID-19)
- Severe respiratory failure,
Exclusion Criteria:
- pregnancy or breast feeding,
- lung bleeding,
- any acute or chronic disease that may be a contraindication to bronchoscopy,
- any diseases of hematopoietic system,
- taking part in other clinical trials