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Hemodynamic Changes Due to Prone Position

Hemodynamic Changes Due to Prone Position

Recruiting
18 years and older
All
Phase N/A

Overview

Perioperative prone position may be associated with hemodynamic instability. The causes of instability have not yet been precisely elucidated. The aim of this study is to demonstrate physiological changes during prone positioning in healthy volunteers .

Description

The prone position could decrease the cardiac index (CI), mainly due to reduction in stroke volume, with little changes in heart rate. Mean arterial pressure (MAP) could be maintained by increased systemic vascular resistance (SVR) in the majority of patients.

The aim of this study is to describe hemodynamic changes in two different surgical prone positions in 10 healthy non-anesthetized volunteers (flat position and using a support system allowing a free abdomen) by non-invasive measurement of hemodynamics (ClearSight, Edwards) and indirectly evaluated intra-abdominal pressure using ultrasound. The ClearSight system provides advanced hemodynamic parameters (cardiac index CI, stroke volume SV, stroke volume variation SVV, systemic vascular resistance SVR, mean arterial pressure MAP) from a finger cuff.

Eligibility

Inclusion Criteria:

  • age >18 years, American Society of Anesthesiologists (ASA) Physical Status Classification I-II, agreement with study participation

Exclusion Criteria:

  • disagreement with study participation, BMI over 40

Study details
    Prone Position
    Hemodynamics Instability

NCT04491331

University Hospital Hradec Kralove

16 February 2024

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