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Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800 an Inhibitor of the Heat Shock Protein HSP90

Preclinical Project on the Traitment of Acute Lymphoblastique Leukemia With NVP-BEP800 an Inhibitor of the Heat Shock Protein HSP90

Recruiting
18-80 years
All
Phase N/A

Overview

NVP-BEP800, a new HSP90 inhibitor, has particularly interesting therapeutic potential and represents hope in cancer pathologies. While it is currently being tested for solid cancers, no preclinical study has yet demonstrated its effectiveness in acute lymphoblastique leukemia (ALL). The investigators wish to study the effects of NVP-BEP800 on two different types of ALL (T and B-ALL).

Eligibility

Inclusion Criteria:

  • Patient suffering from acute lymphoblastic leukaemia whose biological samples are kept at the Biology Technical Platform.

Exclusion Criteria:

  • Patient over 80 years of age

Study details
    Acute T Lymphoblastic Leukemia (T-ALL)
    Acute B Lymphoblastic Leukemia (B-ALL)

NCT04437420

Centre Hospitalier Universitaire Dijon

16 February 2024

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