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Psychotherapy (Accelerated Resolution Therapy) for Cancer Related Trauma and Distress

Psychotherapy (Accelerated Resolution Therapy) for Cancer Related Trauma and Distress

Recruiting
18 years and older
All
Phase N/A

Overview

This trial studies whether a form of psychotherapy called accelerated resolution therapy can help with cancer distress and psychological trauma. Accelerated resolution therapy is an evidence-based therapy for the treatment of depressive symptoms, trauma, and stress-related disorders. This study may provide evidence to support integration of accelerated resolution therapy into psychological treatment of cancer patients, which may decrease cancer related trauma and distress.

Description

PRIMARY OBJECTIVES:

I. Calculate changes, and estimate mean changes, in primary outcomes of psychological trauma and cancer distress over a six week time period while receiving weekly accelerated resolution therapy (ART).

II. Calculate changes, and estimate mean changes, in secondary outcomes of anxiety and depression over a six week period while receiving weekly ART.

III. We will use a qualitative, descriptive design to explore contextual elements of the cancer experience that are consistently distressing and/or psychologically traumatic to more fully inform a future randomized controlled trial (RCT) testing in ART in cancer distress and psychological trauma.

IV. Calculate changes, and estimate mean changes, in secondary outcomes of resilience and symptom distress over a six week period while receiving weekly ART.

OUTLINE

Patients undergo ART over 60-90 minutes once a week for up to 5 sessions.

After completion of study intervention, patients are followed up at 1 week and again at 1 month.

Eligibility

Inclusion Criteria:

  • Able to read, write and understand English
  • Undergone chemotherapy, radiation therapy, chimeric antigen receptor T cells (CAR-T), or bone marrow transplant for a cancer diagnosis within the previous 3 years or have metastatic cancer
  • A mean score of at least 1.1 on the Cancer and Treatment Distress (CTxD) or at least one item rated at a 3 (often true) or 4 (nearly all the time)
  • A minimum score of 3 on the Primary Care-Post Traumatic Stress Disorder Screen (PC-PTSD-5)
  • Denial of suicidal ideation or intent, with no evidence of psychotic behavior
  • Participants must be willing and able to travel to Mayo Clinic outside of normally scheduled visits to participate in the study

Study details
    Hematologic Malignancy
    hematologic neoplasms
    Metastatic Malignant Neoplasm
    hematologic neoplasms
    Malignant Solid Neoplasm

NCT04436835

Mayo Clinic

16 February 2024

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