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Bone-biomarkers of Spinal Cord Injury Patients

Bone-biomarkers of Spinal Cord Injury Patients

Recruiting
20 years and older
All
Phase N/A

Overview

Patients with spinal cord injury have a high prevalence of osteoporosis due to chronic skeletal unloading. Recently, various treatment drugs for osteoporosis have been developed. In particular, romosozumab, a sclerostin inhibitor, has been reported to have a high therapeutic effect as an inhibitor of bone resorption while promoting bone formation. However, there are a few research concerning sclerostin of spinal cord injuries patients. Therefore we want to analyze the change of sclerostin as well as factors indicating bone formation and absorption marker in spinal cord injury patient.

Eligibility

Inclusion Criteria:

  • spinal cord injury patients
  • Functional ambulatory category index of 3 or less

Exclusion Criteria:

  • history of using bone absorption medication within the effective period

Study details
    Osteopenia
    Osteopenia
    Spinal Cord Injury
    Myelopathy
    spinal cord disorders
    Trauma
    wounds
    Osteoporosis
    Osteoporosis
    Bone Diseases
    Bone Diseases
    Bone Resorption
    wounds
    spinal cord disorders

NCT04403256

Yeungnam University Hospital

16 February 2024

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