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Acute Kidney Injury and Renal Outcomes for COVID-19 Patients in Intensive Care Units

Acute Kidney Injury and Renal Outcomes for COVID-19 Patients in Intensive Care Units

Recruiting
18 years and older
All
Phase N/A

Overview

The actual COVID-19 epidemy is an unprecedented healthcare problem. Although acute respiratory distress syndrome is the main organ failure, acute kidney injury (AKI) has appeared to be more frequent and more severe than expected. Some data suggested a potential direct renal tropism of the virus, or undirect injury by "cytokine storm".

The aims of this study are:

  1. To describe incidence, severity and mortality associated with AKI during covid-19 infection in ICU
  2. To identify specific risk factors for AKI
  3. To explore pathophysiologic mechanism of AKI during COVID-19 infection

Eligibility

Inclusion Criteria:

  • Confirmed COVID-19 infection (by qRT-PCR and/or TDM typical lesion)
  • Needing intensive care

Exclusion Criteria:

  • End Stage Renal Disease patients (with pre-existent dialysis)
  • Intensive care support for less than 72h (transfer in conventional unit or death)

Study details
    on Occurrence of Acurate Kidney Injury During Intensive Care Unit
    Abnormalities of Urinary Analysis

NCT04459975

Hospices Civils de Lyon

16 February 2024

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