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Mind-Body Medicine for the Improvement of Quality of Life in Adolescents and Young Adults Coping With Hodgkin Lymphoma

Mind-Body Medicine for the Improvement of Quality of Life in Adolescents and Young Adults Coping With Hodgkin Lymphoma

Recruiting
18-39 years
All
Phase N/A

Overview

This trial studies how well a mind-body intervention works in improving overall quality of life in adolescents and young adults with Hodgkin lymphoma. A meditation based mind-body intervention may help lower distress, depressive symptoms, and anxiety in adolescents and young adults coping with Hodgkin lymphoma.

Description

PRIMARY OBJECTIVE:

I. Examine the feasibility of the mind-body intervention in adolescents and young adults (AYAs) with Hodgkin lymphoma (HL).

SECONDARY OBJECTIVE:

I. Establish the initial intervention efficacy regarding psychological distress and cancer symptoms (tertiary objective) relative to an attention control (AC) group.

EXPLORATORY OBJECTIVE:

I. Explore mediation (e.g., mindfulness, compassion, social connection, inflammatory processes) and moderation (e.g., demographic and medical factors) of the intervention effects.

OUTLINE: Patients are randomized to 1 of 2 groups.

GROUP I: Patients attend meditation group sessions over 75 minutes once weekly for up to 5 weeks.

GROUP II: Patients attend educational group sessions over 75 minutes once weekly for up to 5 weeks.

After completion of study intervention, patients are followed at 6 and 12 weeks.

Eligibility

Inclusion Criteria:

  • Participants diagnosed within 6 months with stage I-IV HL
  • Eastern Cooperative Oncology Group (ECOG) performance status of 2 or below
  • Having access to the internet
  • Able to read, write and speak English

Exclusion Criteria:

  • Major psychiatric or cognitive deficits that would impede the completion of self-report instruments as deemed by the clinical team
  • Regular (self-defined) participation in psychotherapy or a formal cancer support group

Study details
    Lugano Classification Stage I Adult Hodgkin Lymphoma AJCC v8
    Lugano Classification Stage IE Adult Hodgkin Lymphoma AJCC v8
    Lugano Classification Stage II Hodgkin Lymphoma AJCC v8
    Lugano Classification Stage IIE Adult Hodgkin Lymphoma AJCC v8
    Lugano Classification Stage III Hodgkin Lymphoma AJCC v8
    Lugano Classification Stage IV Hodgkin Lymphoma AJCC v8

NCT04270266

M.D. Anderson Cancer Center

16 February 2024

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