Overview
The aim of the study is to compare self-reported gastrointestinal symptoms and intestinal fermentation rates of the study products as measured by breath hydrogen and methane in adult population with self-reported mild abdominal sensitivity to pulses. The study products are a pulse products with two different cereals.
Description
The study is a randomized, controlled, double-blind, cross-over intervention trial. The aim is to recruit 25 subjects to the trial. The study will be conducted with a cross-over setting, where the subjects will go through exposure meals and breath gas measurement two times (two different test products) in a randomized order. The study meals are identical in appearance but differ in fiber content. After study breakfast the breath gases are analyzed every 15 minutes during 8 hours.
Eligibility
Inclusion Criteria:
- Healthy subjects with subjective experience of gut symptoms after consumption of pulses
- Celiac disease and wheat allergy excluded by antigen test
- Age 18-65
- BMI 18,5 - 30
- Normal liver, thyroid and kidney functions
Exclusion Criteria:
- Celiac disease, Crohn's disease, ulcerative colitis or acute diverticulitis
- Any medication affecting the gastrointestinal tract (e.g. laxatives and acid-suppressive drugs)
- Antibiotic treatment within previous 3 months
- Blood donation or participation to another clinical trial within one month prior to study entry