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Anesthesia and Cancer Study: Colon

Anesthesia and Cancer Study: Colon

Recruiting
19-70 years
All
Phase N/A

Overview

This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.

Description

The effect of anesthesia on cancer recurrence and survival is controversial. According to some retrospective studies and preclinical studies, total intravenous anesthesia (TIVA) is suggested to be more favorable than inhalation anesthesia regarding cancer recurrence and survival after surgery. However, there is no randomized controlled study to determine this difference in colon cancer patients.

Eligibility

Inclusion Criteria:

  • adults undergoing surgery to remove colon cancer

Exclusion Criteria:

  • pregnancy
  • colon cancer with invasion to perineum
  • palliative surgery
  • history of diagnosis or surgery for other cancer
  • emergent surgery
  • ASA PS classification 4 and 5
  • refusion to participate in the study
  • allergy to anesthetics

Study details
    Colorectal Cancer
    Colorectal Cancer
    Malignant neoplasm of colon
    Anesthesia
    Anesthesia

NCT04259398

Seoul National University Hospital

16 February 2024

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